| Effect of tamsulosin on the number and intensity of ureteral colic in patients with lower ureteral calculus. | |
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MedLine Citation:
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PMID: 16045553 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: We aimed to objectively determine whether tamsulosin as an alpha(1)-blocker was effective in patients who had ureterolithiasis located in the lower part of the ureter. METHODS: Sixty patients with lower ureteral calculi (juxtavesical or intramural portion) were included in the present study. Conservative treatment, such as hydration and tenoxicam as a non-steroidal anti-inflammatory drug, was given to group 1 (30 patients). Group 2 (30 patients) was given tamsulosin (0.4 mg daily) in addition to the conservative treatment. All patients were followed up and questioned about the numbers and intensity of ureteral colic, and the rates of spontaneous passage after the procedure. RESULTS: Spontaneous passage was observed in 22 of the 30 patients in group 1 (73.3%) and 26 of the 30 patients in group 2 (86.6%). The difference within groups 1 and 2 was not significant (P=0.196). The difference between both groups was not statistically significant either, with the stone diameter being 6 mm (P=0.635) or >6 mm (P=0.407). As group 1 patients were passing their stones, they had more ureteral colic episodes than group 2 patients. This difference was statistically significant and correlated well with the administration of tamsulosin (P=0.038). Group 1 patients reported higher scores according to a visual analog scale than group 2 patients. Also, this difference was statistically significant (P=0.000). CONCLUSIONS: We think that the treatment of alpha(1)-blockers decreased the number of ureteral colic episodes and the intensity of pain during spontaneous passage at the lower ureteral calculi. Also, it will be beneficial to patients' quality of life. |
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Authors:
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Sefa Resim; Hasan Ekerbicer; Ahmet Ciftci |
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Publication Detail:
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Type: Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: International journal of urology : official journal of the Japanese Urological Association Volume: 12 ISSN: 0919-8172 ISO Abbreviation: Int. J. Urol. Publication Date: 2005 Jul |
Date Detail:
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Created Date: 2005-07-27 Completed Date: 2006-01-03 Revised Date: 2006-10-30 |
Medline Journal Info:
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Nlm Unique ID: 9440237 Medline TA: Int J Urol Country: Australia |
Other Details:
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Languages: eng Pagination: 615-20 Citation Subset: IM |
Affiliation:
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Department of Urology, KSU Medical School, Kahramanmaras, Turkey. safarasim@ksu.edu.tr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adrenergic alpha-Antagonists / therapeutic use* Adult Colic / drug therapy*, etiology* Female Follow-Up Studies Humans Male Middle Aged Pain Measurement Prospective Studies Receptors, Adrenergic, alpha-1 / antagonists & inhibitors Sulfonamides / therapeutic use* Treatment Outcome Ureteral Calculi / complications* |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic alpha-Antagonists; 0/Receptors, Adrenergic, alpha-1; 0/Sulfonamides; 106133-20-4/tamsulosin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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