| Effect of synthetic chicken vasoactive intestinal peptide on pancreatic blood flow and on exocrine and endocrine secretions of the pancreas in dogs. | |
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MedLine Citation:
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PMID: 6347571 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This study was undertaken to determine the effect of synthetic chicken vasoactive intestinal peptide (VIP) on pancreatic blood flow, exocrine and endocrine secretions of the pancreas, and biliary secretion in dogs. The effect of synthetic chicken VIP on pancreatic blood flow and systemic arterial pressure was identical to that of natural chicken VIP in dogs. The present study demonstrated that synthetic chicken VIP induces significant increases in pancreatic blood flow, pancreaticobiliary secretion, and blood levels of insulin and glucose in dogs. Both the volume of pancreatic juice and blood levels of insulin were increased in consonance with the increase of pancreatic blood flow. This study suggests that the stimulatory effects of synthetic chicken VIP on exocrine and endocrine secretions of the pancreas may be related to the increased pancreatic blood flow elicited by synthetic chicken VIP. |
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Authors:
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K Inoue; T Kawano; K Shima; T Kim; T Suzuki; T Tobe; M Takeyama; H Yajima |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Digestive diseases and sciences Volume: 28 ISSN: 0163-2116 ISO Abbreviation: Dig. Dis. Sci. Publication Date: 1983 Aug |
Date Detail:
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Created Date: 1983-09-23 Completed Date: 1983-09-23 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 7902782 Medline TA: Dig Dis Sci Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 724-32 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Bicarbonates / analysis Bile / analysis, secretion Blood Glucose / analysis Blood Pressure / drug effects Chickens Dogs Female Gastrointestinal Hormones / pharmacology* Hormones / pharmacology Insulin / blood Male Pancreas / blood supply* Pancreatic Juice / secretion* Regional Blood Flow / drug effects Vasoactive Intestinal Peptide / pharmacology* |
| Chemical | |
Reg. No./Substance:
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0/Bicarbonates; 0/Blood Glucose; 0/Gastrointestinal Hormones; 0/Hormones; 11061-68-0/Insulin; 37221-79-7/Vasoactive Intestinal Peptide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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