Document Detail


Effect of synthetic chicken vasoactive intestinal peptide on pancreatic blood flow and on exocrine and endocrine secretions of the pancreas in dogs.
MedLine Citation:
PMID:  6347571     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study was undertaken to determine the effect of synthetic chicken vasoactive intestinal peptide (VIP) on pancreatic blood flow, exocrine and endocrine secretions of the pancreas, and biliary secretion in dogs. The effect of synthetic chicken VIP on pancreatic blood flow and systemic arterial pressure was identical to that of natural chicken VIP in dogs. The present study demonstrated that synthetic chicken VIP induces significant increases in pancreatic blood flow, pancreaticobiliary secretion, and blood levels of insulin and glucose in dogs. Both the volume of pancreatic juice and blood levels of insulin were increased in consonance with the increase of pancreatic blood flow. This study suggests that the stimulatory effects of synthetic chicken VIP on exocrine and endocrine secretions of the pancreas may be related to the increased pancreatic blood flow elicited by synthetic chicken VIP.
Authors:
K Inoue; T Kawano; K Shima; T Kim; T Suzuki; T Tobe; M Takeyama; H Yajima
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Digestive diseases and sciences     Volume:  28     ISSN:  0163-2116     ISO Abbreviation:  Dig. Dis. Sci.     Publication Date:  1983 Aug 
Date Detail:
Created Date:  1983-09-23     Completed Date:  1983-09-23     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7902782     Medline TA:  Dig Dis Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  724-32     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Bicarbonates / analysis
Bile / analysis,  secretion
Blood Glucose / analysis
Blood Pressure / drug effects
Chickens
Dogs
Female
Gastrointestinal Hormones / pharmacology*
Hormones / pharmacology
Insulin / blood
Male
Pancreas / blood supply*
Pancreatic Juice / secretion*
Regional Blood Flow / drug effects
Vasoactive Intestinal Peptide / pharmacology*
Chemical
Reg. No./Substance:
0/Bicarbonates; 0/Blood Glucose; 0/Gastrointestinal Hormones; 0/Hormones; 11061-68-0/Insulin; 37221-79-7/Vasoactive Intestinal Peptide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  In-continuity gastrointestinal stapling.
Next Document:  Light microscopic morphometric analysis of rat ileal mucosa. I. Component quantitation of IgA-contai...