Document Detail


Effect of supplemental oral L-arginine on exercise capacity in patients with stable angina pectoris.
MedLine Citation:
PMID:  9264427     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A randomized, double-blind, placebo-controlled study in patients with clinical symptoms of stable angina pectoris and healed myocardial infarction (n = 22) has shown that oral supplementation with L-arginine (6 g/day for 3 days) increases exercise capacity (tested on a Marquette case 12 treadmill according to the modified Bruce protocol). Results suggest that the inefficient L-arginine/nitric oxide system contributes to limitation of myocardial perfusion and/or peripheral vasodilation during maximum exercise in patients with stable angina pectoris.
Authors:
L Ceremuzyński; T Chamiec; K Herbaczyńska-Cedro
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  The American journal of cardiology     Volume:  80     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1997 Aug 
Date Detail:
Created Date:  1997-09-04     Completed Date:  1997-09-04     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  331-3     Citation Subset:  AIM; IM    
Affiliation:
Department of Cardiology, Postgraduate Medical School, and Medical Research Centre, Polish Academy of Sciences, Warsaw.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Angina Pectoris / physiopathology*
Arginine / pharmacology*
Double-Blind Method
Exercise Tolerance / drug effects*
Female
Humans
Male
Middle Aged
Vasodilation / drug effects
Chemical
Reg. No./Substance:
74-79-3/Arginine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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