Document Detail


Effect of somatostatin on the secretin-induced gastric secretions of pepsin and mucus in cats.
MedLine Citation:
PMID:  6123137     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The effect of somatostatin 14 on gastric stimulation produced by secretin was determined in 6 conscious cats equipped with a gastric fistula and a denervated fundic pouch. Somatostatin strongly inhibited the basal and secretin-induced pepsin secretion. It did not, however, inhibit the secretin-induced mucus secretion, even though it decreased the basal mucus secretion. During somatostatin administration, the secretagogue effect of secretin on mucus secretion might be dissociated from its stimulatory action on pepsin secretion.
Authors:
M Vagne; C Roche; J A Chayvialle; C Gespach
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Regulatory peptides     Volume:  3     ISSN:  0167-0115     ISO Abbreviation:  Regul. Pept.     Publication Date:  1982 Mar 
Date Detail:
Created Date:  1982-07-19     Completed Date:  1982-07-19     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  8100479     Medline TA:  Regul Pept     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  183-91     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Cats
Dose-Response Relationship, Drug
Female
Fucose / secretion
Galactose / secretion
Gastric Juice / analysis,  secretion
Gastric Mucosa / secretion*
Male
Mucus / secretion*
Pepsin A / secretion*
Secretin / pharmacology*
Somatostatin / pharmacology*
Chemical
Reg. No./Substance:
1393-25-5/Secretin; 26566-61-0/Galactose; 3713-31-3/Fucose; 51110-01-1/Somatostatin; EC 3.4.23.1/Pepsin A

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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