| Effect of sodium bicarbonate on muscle metabolism during intense endurance cycling. | |
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MedLine Citation:
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PMID: 11932569 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION: Sodium bicarbonate (NaHCO3) ingestion has been shown to increase both muscle glycogenolysis and glycolysis during brief submaximal exercise. These changes may be detrimental to performance during more prolonged, exhaustive exercise. This study examined the effect of NaHCO3 ingestion on muscle metabolism and performance during intense endurance exercise of approximately 60 min in seven endurance-trained men. METHODS: Subjects ingested 0.3 g.kg-1 body mass of either NaHCO3 or CaCO3 (CON) 2 h before performing 30 min of cycling exercise at 77 +/- 1% .VO(2peak) followed by completion of 469 +/- 21 kJ as quickly as possible (approximately 30 min, approximately 80% .VO(2peak)). RESULTS: Immediately before, and throughout exercise, arterialized-venous plasma HCO3- concentrations were higher (P < 0.05) whereas plasma and muscle H+ concentrations were lower (P < 0.05) in NaHCO3 compared with CON. Blood lactate concentrations were higher (P < 0.05) during exercise in NaHCO3, but there was no difference between trials in muscle glycogen utilization or muscle lactate content during exercise. Reductions in PCr and ATP and increases in muscle Cr during exercise were also unaffected by NaHCO3 ingestion. Accordingly, exercise performance time was not different between treatments. CONCLUSION: NaHCO3 ingestion resulted in a small muscle alkalosis but had no effect on muscle metabolism or intense endurance exercise performance in well-trained men. |
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Authors:
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Terry J Stephens; Michael J McKenna; Benedict J Canny; Rodney J Snow; Glenn K McConell |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Medicine and science in sports and exercise Volume: 34 ISSN: 0195-9131 ISO Abbreviation: Med Sci Sports Exerc Publication Date: 2002 Apr |
Date Detail:
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Created Date: 2002-04-04 Completed Date: 2002-04-30 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8005433 Medline TA: Med Sci Sports Exerc Country: United States |
Other Details:
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Languages: eng Pagination: 614-21 Citation Subset: IM; S |
Affiliation:
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Department of Physiology, Monash University, Clayton, 3800 Victoria, Australia. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Oral Adult Alkalosis / metabolism Bicarbonates / blood Bicycling / physiology* Glycogen / metabolism Humans Hydrogen-Ion Concentration Lactic Acid / blood Male Muscle, Skeletal / metabolism* Physical Endurance / physiology* Physical Fitness / physiology Sodium Bicarbonate / administration & dosage, pharmacology* Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Bicarbonates; 144-55-8/Sodium Bicarbonate; 50-21-5/Lactic Acid; 9005-79-2/Glycogen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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