Document Detail

Effect of smoking one cigarette on antioxidant metabolites in the saliva of healthy smokers.
MedLine Citation:
PMID:  10401526     Owner:  NLM     Status:  MEDLINE    
Concentrations of glutathione, uric acid and total antioxidant activity, expressed as Trolox (a water-soluble vitamin E analogue) equivalent, were measured in the saliva of healthy non-smokers and smokers before and just after smoking a single cigarette. There was no statistically significant difference between smokers and non-smokers in uric acid concentrations and total radical-trapping antioxidant capacity, but glutathione concentrations were significantly (p < 0.05) higher in smokers. Smoking of a single cigarette induced a significant reduction in glutathione concentration (p < 0.05). Salivary antioxidant power may affect individual sensitivity toward tobacco stress.
B Zappacosta; S Persichilli; P De Sole; A Mordente; B Giardina
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of oral biology     Volume:  44     ISSN:  0003-9969     ISO Abbreviation:  Arch. Oral Biol.     Publication Date:  1999 Jun 
Date Detail:
Created Date:  1999-09-24     Completed Date:  1999-09-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0116711     Medline TA:  Arch Oral Biol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  485-8     Citation Subset:  D; IM    
Istituto di Chimica e Chimica Clinica, CNR Centro Chimica dei Recettori, Università Cattolica del Sacro Cuore, Rome, Italy.
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MeSH Terms
Antioxidants / metabolism*
Chromatography, High Pressure Liquid
Free Radical Scavengers / metabolism
Glutathione / metabolism
Indicators and Reagents
Middle Aged
Peroxidase / metabolism
Saliva / metabolism*
Smoking / metabolism*
Sulfonic Acids
Uric Acid / metabolism
Reg. No./Substance:
0/Antioxidants; 0/Benzothiazoles; 0/Free Radical Scavengers; 0/Indicators and Reagents; 0/Sulfonic Acids; 28752-68-3/2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid; 69-93-2/Uric Acid; 70-18-8/Glutathione; EC

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