| Effect of smoking cessation intervention on results of acute fracture surgery: a randomized controlled trial. | |
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MedLine Citation:
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PMID: 20516308 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Tobacco smoking is a major health and economic concern and is also known to have a significant negative effect on surgical outcomes. The benefits of a smoking cessation intervention prior to elective orthopaedic surgery have been evaluated previously. Our aim was to assess whether a smoking cessation program, initiated during the acute hospitalization period and carried out for six weeks, could reduce the number of complications following emergency surgical treatment of fractures. METHODS: In a multicenter, single-blinded, randomized, controlled clinical trial, 105 smokers with a fracture of the lower or upper extremity that needed acute surgical treatment were randomized to an intervention group (n = 50) or a control group (n = 55). The intervention group was offered a standardized smoking cessation program for six weeks, and all patients were followed at two to three weeks, four weeks, and six to twelve weeks. RESULTS: The proportion of patients with at least one postoperative complication was significantly larger in the control group than it was in the intervention group (38% and 20%, respectively; p = 0.048). The development of two or more postoperative complications was also more common among the controls (p = 0.039). The rates of superficial wound infection, the most frequently recorded complication in both groups, were 20% and 8%, but this difference was not significant. A secondary analysis showed that the odds of having a complication were 2.51 times (95% confidence interval, 0.96 to 6.9 times) higher in the control group than in the intervention group, but this difference was not significant. CONCLUSIONS: Our results indicate that a smoking cessation intervention program during the first six weeks after acute fracture surgery decreases the risk of postoperative complications. |
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Authors:
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Hans Nåsell; Johanna Adami; Eva Samnegård; Hanne Tønnesen; Sari Ponzer |
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Publication Detail:
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Type: Journal Article; Multicenter Study; Randomized Controlled Trial |
Journal Detail:
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Title: The Journal of bone and joint surgery. American volume Volume: 92 ISSN: 1535-1386 ISO Abbreviation: J Bone Joint Surg Am Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-06-02 Completed Date: 2010-07-08 Revised Date: 2010-10-25 |
Medline Journal Info:
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Nlm Unique ID: 0014030 Medline TA: J Bone Joint Surg Am Country: United States |
Other Details:
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Languages: eng Pagination: 1335-42 Citation Subset: AIM; IM |
Affiliation:
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Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, S-118 83 Stockholm, Sweden. nasell@sodersjukhuset.se |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Emergencies Extremities / injuries, surgery* Female Fracture Fixation / adverse effects* Fracture Healing Humans Male Middle Aged Postoperative Complications / prevention & control Single-Blind Method Smoking / adverse effects* Smoking Cessation* |
| Comments/Corrections | |
Comment In:
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Z Orthop Unfall. 2010 Sep;148(5):514
[PMID:
20931701
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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