Document Detail


Effect of small deep hemispheric infarction on the ipsilateral cortical blood flow in man.
MedLine Citation:
PMID:  3966268     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The effect of small, deep ischemic lesions on the ipsilateral cortical circulation was investigated in 10 patients with persistent mild or moderate neurological deficits due to infarcts in the internal capsule. rCBF studies by the 133Xe intracarotid injection method were performed 14-180 days after the onset of the infarction. The rCBF functional image was made up from the data of 133Xe dynamic images measured by an Anger-type gamma camera and the rCBF values were calculated by the initial slope method. The average value of mean rCBFs (mCBF) in 10 patients was 44.9 +/- 7.1 ml/100g/min (average PaCO2; 39.9 +/- 4.3 mm Hg). In the rCBF functional images, a focal hypoperfusion area was observed in all cases and localized around the central sulcus, especially in the precentral and central areas. Significant decreases of mCBF and the tendency to decrease of the rCBFs in the hypoperfusion focus were noted in the patients with the larger infarcts in comparison with those with the smaller ones. These results suggest that a small, deep ischemic lesion such as a capsular infarct may have remote effects on the ipsilateral cortical circulation, due probably to the damage of a number of fibers passing through the lesion.
Authors:
T Takano; K Kimura; M Nakamura; R Fukunaga; M Kusunoki; H Etani; M Matsumoto; S Yoneda; H Abe
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Stroke; a journal of cerebral circulation     Volume:  16     ISSN:  0039-2499     ISO Abbreviation:  Stroke     Publication Date:    1985 Jan-Feb
Date Detail:
Created Date:  1985-02-19     Completed Date:  1985-02-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0235266     Medline TA:  Stroke     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  64-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Blood Flow Velocity
Cerebral Cortex / blood supply*
Cerebral Infarction / physiopathology*
Female
Hemiplegia / physiopathology*
Humans
Male
Middle Aged
Perfusion
Regional Blood Flow
Xenon Radioisotopes / diagnostic use
Chemical
Reg. No./Substance:
0/Xenon Radioisotopes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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