Document Detail

Effect of silver nitrate on pregnancy termination in cynomolgus monkeys.
MedLine Citation:
PMID:  7250398     Owner:  NLM     Status:  MEDLINE    
The effect of intrauterine injection of 1% silver nitrate on pregnancy was studied in 13 cynomolgus monkeys. The monkeys received, in a random manner, intrauterine injections of 1 ml of either 1% silver nitrate (n = 7) or 0.9% NaCl solution (n = 6) between days 27 and 43 of pregnancy. Silver nitrate injection resulted in vaginal bleeding, beginning 1 or 2 days after treatment, that lasted for an average of 5.3 days. In all of these cases, pregnancy was terminated. Injection of normal saline had variable sequelae, but four of six monkeys were delivered of healthy offspring. All of the silver nitrate-treated animals recycled and, after remating, two of the seven subsequently became pregnant again and were delivered of normal healthy infants. This study demonstrates the efficacy of intrauterine injection of 1% silver nitrate in terminating early pregnancy.
N H Dubin; T H Parmley; R T Cox; T M King
Related Documents :
21849598 - The salmon in pregnancy study: study design, subject characteristics, maternal fish and...
21645918 - Changes in d-dimer levels after cesarean section in women with singleton and twin pregn...
21954848 - Cardiac performance is impaired in morbidly obese pregnant females.
21900148 - A randomized controlled trial investigating the effects of a low-glycemic index diet on...
18818938 - Pregnancy in chronic renal insufficiency: single centre experience from north india.
12368978 - Pregnancy with prolonged fetal exposure to an angiotensin-converting enzyme inhibitor.
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Fertility and sterility     Volume:  36     ISSN:  0015-0282     ISO Abbreviation:  Fertil. Steril.     Publication Date:  1981 Jul 
Date Detail:
Created Date:  1981-09-22     Completed Date:  1981-09-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  106-9     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Abortifacient Agents*
Abortifacient Agents, Nonsteroidal*
Abortion, Induced / methods*
Macaca fascicularis
Pregnancy, Animal*
Silver Nitrate / pharmacology*
Reg. No./Substance:
0/Abortifacient Agents; 0/Abortifacient Agents, Nonsteroidal; 7761-88-8/Silver Nitrate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Postcoital, Vaginal, spermicidal potency of formulations: the Macaca arctoides (stumptailed macaque)...
Next Document:  Ultrastructural changes in endometriotic tissue during danazol treatment.