Document Detail


Effect of sildenafil citrate on penile erection of rhesus macaques.
MedLine Citation:
PMID:  15273873     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIM: To examine the effect of sildenafil citrate on penile erection of male rhesus macaque. METHODS: Twenty Macaca mulatta were divided into the sildenafil treated and the control groups of 10 animals each. The penile size, the corpus cavernosal electromyogram (EMG) and the intra-corpus cavernosal pressure (ICP) were determined. RESULTS: The diameter of penis and the ICP were significantly increased and the corpus cavernosal EMG significantly reduced in the sildenafil group. CONCLUSION: Sildenafil citrate increases the penile size and ICP and reduces the corpus cavernosal EMG in male rhesus macaque.
Authors:
Xun-Bin Huang; Cheng-Liang Xiong; Cheng-Gao Yu; Jie-Ling Zhou; Ji-Yun Shen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Asian journal of andrology     Volume:  6     ISSN:  1008-682X     ISO Abbreviation:  Asian J. Androl.     Publication Date:  2004 Sep 
Date Detail:
Created Date:  2004-07-26     Completed Date:  2005-03-28     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  100942132     Medline TA:  Asian J Androl     Country:  China    
Other Details:
Languages:  eng     Pagination:  233-5     Citation Subset:  IM    
Affiliation:
Center for Reproductive Medicine, Tongji Medical College, Huazhong University of Science and Technology, 13 Hang Kong Road, Wuhan 430030, China. huangxb@mails.tjmu.edu.cn
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MeSH Terms
Descriptor/Qualifier:
Animals
Electromyography
Macaca mulatta
Male
Penile Erection / drug effects*,  physiology
Penis / anatomy & histology,  drug effects
Piperazines / pharmacology*
Purines
Sulfones
Vasodilator Agents / pharmacology*
Chemical
Reg. No./Substance:
0/Piperazines; 0/Purines; 0/Sulfones; 0/Vasodilator Agents; 139755-83-2/sildenafil

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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