| Effect of secretin on intestinal lymph flow and composition in the rat. | |
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MedLine Citation:
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PMID: 6910730 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effects of natural porcine and synthetic secretin, given by intravenous bolus or infusion, on intestinal lymph flow and protein composition in unanaesthetized rats were studied. Both forms of secretin increased lymph flow and protein output from the lymph fistula; dose-response relationships were determined. No change was observed in protein concentration in lymph or in the relative concentrations of large and small protein molecules during secretin-induced enhanced lymph flow, compared with the basal state. These results are in keeping with an increase in the functional exchange vessel area of the small intestine produced by secretin. It is possible that secretin may play a part in the hyperaemia and augmented intestinal lymph flow which occurs in the post-prandial period. |
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Authors:
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J A Lawrence; D Bryant; K B Roberts; J A Barrowman |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Quarterly journal of experimental physiology (Cambridge, England) Volume: 66 ISSN: 0144-8757 ISO Abbreviation: Q J Exp Physiol Publication Date: 1981 Jul |
Date Detail:
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Created Date: 1981-09-15 Completed Date: 1981-09-15 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 8206873 Medline TA: Q J Exp Physiol Country: SCOTLAND |
Other Details:
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Languages: eng Pagination: 297-305 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Intestines / physiology* Lymph / analysis, drug effects*, physiology Male Proteins / analysis Rats Secretin / pharmacology* Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Proteins; 1393-25-5/Secretin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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