Document Detail

Effect of salt intake on blood pressure in diabetic hypertensive patients in Saudi Arabia.
MedLine Citation:
PMID:  17530109     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To understand the impact of salt intake on blood pressure and to assess the application of international management guidelines in Saudi diabetic hypertensive patients. METHODS: We recruited 112 consecutive diabetic hypertensive patients visiting the diabetic and nephrology clinic at the King Khalid University Hospital between July 2005 and January 2006. Participants received complete medical assessment and their 24 hours urine sodium was measured. Patients on diuretics were excluded from the study. RESULTS: A significant correlation between 24 hours urine sodium and diastolic blood pressure concentration was observed (r = 0.25, p=0.04) but not with systolic blood pressure (r =0.06, p=0.6) or 24 hours urine protein (r =0.06, p=0.63). Approximately 15% of the patients had an glycosylated hemoglobin (A1C) of between 7-8% while 41.2% had an A1C of >8 (suboptimal group for glycemic control). Low-density lipoprotein (LDL) cholesterol in only 37.5% of the patients was within the desired goal (<2.4 mmol/l). Whereas only 24.8% of the patients achieved the goal of systolic and diastolic BP of <130/80 mm Hg. CONCLUSION: Modest salt restriction has possible adjuvant effect to pharmacologic treatment to enhance blood pressure control. However, a majority of the Saudi diabetic patients with hypertension and hyperlipidemia are inadequately treated.
Abdulkareem Alsuwaida
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Saudi medical journal     Volume:  28     ISSN:  0379-5284     ISO Abbreviation:  Saudi Med J     Publication Date:  2007 Jun 
Date Detail:
Created Date:  2007-05-28     Completed Date:  2007-07-27     Revised Date:  2008-06-23    
Medline Journal Info:
Nlm Unique ID:  7909441     Medline TA:  Saudi Med J     Country:  Saudi Arabia    
Other Details:
Languages:  eng     Pagination:  909-12     Citation Subset:  IM    
Department of Nephrology, King Saud University, Riyadh, Kingdom of Saudi Arabia.
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MeSH Terms
Blood Pressure / drug effects*
Diabetes Complications / physiopathology*
Hypertension / physiopathology*
Middle Aged
Saudi Arabia
Sodium Chloride, Dietary / pharmacology*
Reg. No./Substance:
0/Sodium Chloride, Dietary

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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