|Effect of right ventricular function and pulmonary pressures on heart failure prognosis.|
|PMID: 20377809 Owner: NLM Status: MEDLINE|
|The relationship of right ventricular function and pulmonary systolic pressure in patients with congestive heart failure was evaluated to risk-stratify them. The study included 147 consecutive patients with symptomatic heart failure who underwent clinical and laboratory examination and echocardiography including Doppler tissue echocardiography. They were followed for a mean of 11.2+/-6.4 months. During follow-up, 16 patients died and 45 patients had nonfatal cardiac events. There were 60 readmissions for heart failure. Pulmonary artery systolic pressure and right ventricular systolic function were inversely related (r(2)=0.66, P<.001). On Cox multivariate survival analysis, early worsening of pulmonary arterial pressures was an independent prognostic predictor (hazard ratio, 0.44; confidence interval, 0.28-0.91, P=.024). The patients with pulmonary hypertension and right ventricular systolic dysfunction had the worst prognosis. The assessments of right ventricular function help to risk-stratify patients with heart failure. The early worsening of pulmonary hypertension is a powerful predictor of worse prognosis.|
|Srilakshmi M Adhyapak|
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|Type: Journal Article|
|Title: Preventive cardiology Volume: 13 ISSN: 1751-7141 ISO Abbreviation: Prev Cardiol Publication Date: 2010|
|Created Date: 2010-04-09 Completed Date: 2010-07-16 Revised Date: -|
Medline Journal Info:
|Nlm Unique ID: 9813731 Medline TA: Prev Cardiol Country: United States|
|Languages: eng Pagination: 72-7 Citation Subset: IM|
|Department of Cardiology, St. John's Medical College Hospital, Bangalore, India. email@example.com|
|APA/MLA Format Download EndNote Download BibTex|
Aged, 80 and over
Analysis of Variance
Heart Failure / mortality*, physiopathology*, ultrasonography
Lung / physiopathology, ultrasonography
Proportional Hazards Models
Pulmonary Artery / physiopathology*, ultrasonography
Pulmonary Wedge Pressure*
Statistics as Topic
Ventricular Function, Right*
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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