| Effect of right ventricular function and pulmonary pressures on heart failure prognosis. | |
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MedLine Citation:
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PMID: 20377809 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The relationship of right ventricular function and pulmonary systolic pressure in patients with congestive heart failure was evaluated to risk-stratify them. The study included 147 consecutive patients with symptomatic heart failure who underwent clinical and laboratory examination and echocardiography including Doppler tissue echocardiography. They were followed for a mean of 11.2+/-6.4 months. During follow-up, 16 patients died and 45 patients had nonfatal cardiac events. There were 60 readmissions for heart failure. Pulmonary artery systolic pressure and right ventricular systolic function were inversely related (r(2)=0.66, P<.001). On Cox multivariate survival analysis, early worsening of pulmonary arterial pressures was an independent prognostic predictor (hazard ratio, 0.44; confidence interval, 0.28-0.91, P=.024). The patients with pulmonary hypertension and right ventricular systolic dysfunction had the worst prognosis. The assessments of right ventricular function help to risk-stratify patients with heart failure. The early worsening of pulmonary hypertension is a powerful predictor of worse prognosis. |
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Authors:
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Srilakshmi M Adhyapak |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Preventive cardiology Volume: 13 ISSN: 1751-7141 ISO Abbreviation: Prev Cardiol Publication Date: 2010 |
Date Detail:
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Created Date: 2010-04-09 Completed Date: 2010-07-16 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9813731 Medline TA: Prev Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 72-7 Citation Subset: IM |
Affiliation:
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Department of Cardiology, St. John's Medical College Hospital, Bangalore, India. srili2881967@yahoo.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Analysis of Variance Confidence Intervals Echocardiography Echocardiography, Doppler Female Heart Failure / mortality*, physiopathology*, ultrasonography Humans Lung / physiopathology, ultrasonography Male Middle Aged Multivariate Analysis Prognosis Proportional Hazards Models Pulmonary Artery / physiopathology*, ultrasonography Pulmonary Wedge Pressure* ROC Curve Respiration Risk Factors Statistics as Topic Stroke Volume Survival Analysis Systole Ventricular Function, Right* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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