| Effect of respiratory muscle training on maximum aerobic power in normoxia and hypoxia. | |
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MedLine Citation:
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PMID: 20156604 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To assess the effects of respiratory muscle training (RMT) on maximum oxygen uptake (VO2max) in normoxia and hypoxia, 9 healthy males (age 24 +/- 4 years; stature 1.75 +/- 0.08 m; body mass 72 +/- 9 kg; mean +/- SD) performed on different days maximal incremental tests on a cycle ergometer in normoxia and normobaric hypoxia (FIO2=0.11), before and after 8 weeks of RMT (5 days/week). During each test, gas exchange variables were measured breath-by-breath by a metabolimeter. After RMT, no changes in cardiorespiratory and metabolic variables were detected at maximal exercise in normoxia. On the contrary, in hypoxia expired and alveolar ventilation (V(E(and V(A), respectively) at maximal exercise were significantly higher than pre-training condition (+12 and +13%, respectively; P < 0.05). Accordingly, alveolar O2 partial pressure (PAO2) after RMT significantly increased by approximately 10%. Nevertheless, arterial PO2 and VO2max did not change with respect to pre-training condition. In conclusion, RMT improved respiratory function but did not have any effect on VO2max, neither under normoxic nor hypoxic condition. In hypoxia, the significant increase in V(E) and V(A) at maximum exercise after training lead to higher alveolar but not arterial PO2 values, revealing an increased A-a gradient. This result, according to the theoretical models of VO2max limitation, seems to contradict the lack of VO2max increase in hypoxia, suggesting a possible role of increased ventilation-perfusion mismatch. |
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Authors:
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Fabio Esposito; Eloisa Limonta; Giampiero Alberti; Arsenio Veicsteinas; Guido Ferretti |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't Date: 2010-02-13 |
Journal Detail:
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Title: Respiratory physiology & neurobiology Volume: 170 ISSN: 1878-1519 ISO Abbreviation: Respir Physiol Neurobiol Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-03-23 Completed Date: 2010-06-28 Revised Date: 2010-09-20 |
Medline Journal Info:
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Nlm Unique ID: 101140022 Medline TA: Respir Physiol Neurobiol Country: Netherlands |
Other Details:
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Languages: eng Pagination: 268-72 Citation Subset: IM |
Copyright Information:
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Copyright 2010 Elsevier B.V. All rights reserved. |
Affiliation:
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Department of Sport, Nutrition and Health Sciences, University of Milan, Via G. Colombo 71, I-20133 Milan, Italy. fabio.esposito@unimi.it |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anoxia / physiopathology, rehabilitation* Breathing Exercises* Carbon Dioxide / blood Exercise / physiology* Hemoglobins / metabolism Humans Male Oxygen / blood Oxygen Consumption / physiology Physical Exertion / physiology* Respiratory Function Tests / methods Respiratory Muscles / physiopathology* Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Hemoglobins; 124-38-9/Carbon Dioxide; 7782-44-7/Oxygen |
| Comments/Corrections | |
Comment In:
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Respir Physiol Neurobiol. 2010 Sep 30;173(2):113-4; author reply 115-7
[PMID:
20667517
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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