Document Detail

Effect of resistance training on arterial wave reflection and brachial artery reactivity in normotensive postmenopausal women.
MedLine Citation:
PMID:  17394009     Owner:  NLM     Status:  MEDLINE    
Large elastic artery stiffness increases with age and menopause is a mitigating factor in women. High-intensity resistance training (RT) increases arterial stiffness in young men and women. However, the effects of moderate intensity RT on central aortic pressure wave reflection in healthy postmenopausal women are unknown. Healthy sedentary normotensive postmenopausal women were randomly assigned to either 18 weeks (2 days/week) of RT (RES n = 13) or aerobic training (AER n = 10). Central aortic pressure wave reflection and brachial artery reactivity were assessed before and after training. Central aortic pressure wave reflection was evaluated by measuring aortic augmentation index (AI(a)) and round trip travel time (Deltat (p)) of the reflected arterial pressure wave using applanation tonometry. Brachial artery reactivity was assessed using brachial artery flow mediated dilation (FMD). Eighteen weeks of RT did not change AI(a) (28.9 +/- 1.9 vs. 28.5 +/- 1.9%; mean +/- S.E.M.) or Deltat (p) (140.6 +/- 2.4 vs. 141.2 +/- 2.1 ms). In contrast, the AER group showed a decrease in AI(a) from 28.8 +/- 2.1 to 25.1 +/- 1.4% (P < 0.05) and an increase in Deltat (p) from 137.3 +/- 2.5 to 144.6 +/- 2.9 ms (P < 0.05). Brachial FMD did not significantly change in either group following training. This prospective, randomized study demonstrated that moderate intensity whole body RT in previously sedentary, normotensive postmenopausal women does not alter central aortic pressure wave reflection.
Darren P Casey; Gary L Pierce; Kathy S Howe; Mark C Mering; Randy W Braith
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial     Date:  2007-03-30
Journal Detail:
Title:  European journal of applied physiology     Volume:  100     ISSN:  1439-6319     ISO Abbreviation:  Eur. J. Appl. Physiol.     Publication Date:  2007 Jul 
Date Detail:
Created Date:  2007-05-14     Completed Date:  2007-10-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100954790     Medline TA:  Eur J Appl Physiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  403-8     Citation Subset:  IM    
Center for Exercise Science, Department of Applied Physiology and Kinesiology, College of Health and Human Performance, University of Florida, PO Box 118206, Gainesville, FL 32611, USA.
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MeSH Terms
Aorta / physiology
Blood Pressure / physiology
Brachial Artery / physiology*
Exercise / physiology*
Heart Rate / physiology
Middle Aged
Muscle Strength / physiology*
Postmenopause / physiology*
Prospective Studies
Regional Blood Flow
Weight Lifting / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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