| Effect of repeated doses of dexamethasone on the incidence and severity of respiratory distress syndrome in multifetal gestation between 24 and 34 weeks. | |
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MedLine Citation:
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PMID: 11549860 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The objective of the study was to evaluate the effects of antenatal corticosteroid therapy in multiple pregnancy on the incidence and severity of respiratory distress syndrome (RDS). Twenty-two women with twin, 12 with triplet and 2 with quadruplet pregnancies and an emergency group of 20 mothers with twin pregnancies, who only had one course of dexamethasone, were compared with controls. Corticosteroid therapy was associated with a reduction in moderate to severe RDS in all groups (twins p < 0.01, triplets and quadruplets p < 0.008) and the emergency group with dexamethasone therapy (p < 0.036) when compared to their individual controls. Dexamethasone reduced the duration of stay in the neonatal intensive care unit of the emergency twin group (p < 0.01). Neonatal birth weights were significantly less in all groups treated with repeated doses in comparison to the controls. |
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Authors:
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M K Al-Yatama; M Al Essa; A E Omu; I Al-Shamali; P Egbase; N Rashwan |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Gynecologic and obstetric investigation Volume: 52 ISSN: 0378-7346 ISO Abbreviation: Gynecol. Obstet. Invest. Publication Date: 2001 |
Date Detail:
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Created Date: 2001-09-10 Completed Date: 2001-12-04 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7900587 Medline TA: Gynecol Obstet Invest Country: Switzerland |
Other Details:
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Languages: eng Pagination: 26-33 Citation Subset: IM |
Copyright Information:
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Copyright 2001 S. Karger AG, Basel |
Affiliation:
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Department of Obstetrics and Gynecology, Faculty of Medicine, Kuwait University, Safat, Kuwait. sobha@hsc.kuniv.edu.kw |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenal Cortex Hormones
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administration & dosage* Dexamethasone / administration & dosage* Female Humans Infant, Newborn Kuwait Pregnancy Pregnancy, Multiple / drug effects* Respiratory Distress Syndrome, Newborn / drug therapy* |
| Chemical | |
Reg. No./Substance:
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0/Adrenal Cortex Hormones; 50-02-2/Dexamethasone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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