| Effect of regional myocardial perfusion abnormalities on regional myocardial early diastolic function in patients with hypertrophic cardiomyopathy. | |
| | |
MedLine Citation:
|
PMID: 9559969 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Nonuniform hypertrophy of the left ventricle is an important factor in regional diastolic dysfunction in patients with hypertrophic cardiomyopathy (HCM). However, the effect of myocardial perfusion abnormalities on regional diastolic dysfunction has not been established in patients with HCM. We investigated the relationship between regional myocardial perfusion abnormalities and regional early diastolic function in 31 patients with HCM and 8 control patients. Short-axis images of the left ventricle recorded by cine magnetic resonance imaging were divided into ten blocks. The time-to-peak-wall-thickness-thinning rate (TPWR) and the wall thickness were measured in each block. Of the 310 blocks from the patients with HCM, 242 (78%) showed normal thallium-201 uptake (group 1), 40 (13%) showed slightly decreased uptake (group 2), and 28 (9%) showed markedly decreased uptake (group 3). There was no difference in the regional wall thickness among the three groups. The TPWR was longer in patients with HCM than in control patients. It was significantly longer in group 3 (190+/-45ms) than in group 1 (167+/-36 ms) and group 2 (160+/-31 ms). (P < 0.01). The linear regression slope of the relationship between the TPWR and the regional wall thickness was significantly steeper in group 3 than in groups 1 and 2 (P < 0.05). In conclusion, abnormalities in regional myocardial perfusion, in addition to regional hypertrophy, contributed to the regional early diastolic dysfunction in patients with HCM. |
| | |
Authors:
|
H Yamanari; M Kakishita; Y Fujimoto; K Hashimoto; T Kiyooka; Y Katayama; F Otsuka; T Emori; S Uchida; T Ohe |
Related Documents
:
|
11676949 - Plasma nitric oxide level in heart failure secondary to left ventricular diastolic dysf... 21270699 - Correlation of preoperative deformity magnitude and pulmonary function tests in adolesc... 10669669 - Left ventricular thrombus and subsequent thromboembolism in patients with severe systol... 16999689 - Left and right ventricular function is impaired in behçet's disease. 122789 - Ultrastructure of crista supraventricularis muscle in patients with congenital heart di... 20959879 - Left atrial size and force in patients with systolic chronic heart failure: comparison ... 10401789 - Anti-myelin-associated glycoprotein antibodies predict the development of neuropathy in... 18463349 - Approach to the patient with a positive serum thyroglobulin and a negative radioiodine ... 3827679 - Trimodal evoked potentials compared with magnetic resonance imaging in the diagnosis of... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Heart and vessels Volume: 12 ISSN: 0910-8327 ISO Abbreviation: Heart Vessels Publication Date: 1997 |
Date Detail:
|
Created Date: 1998-05-27 Completed Date: 1998-05-27 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8511258 Medline TA: Heart Vessels Country: JAPAN |
Other Details:
|
Languages: eng Pagination: 192-8 Citation Subset: IM |
Affiliation:
|
Department of Cardiovascular Medicine, Okayama University Medical School, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Cardiomyopathy, Hypertrophic / physiopathology*, radionuclide imaging* Diastole / physiology* Female Hemodynamics Humans Magnetic Resonance Imaging, Cine Male Middle Aged Myocardium / metabolism* Thallium Radioisotopes / diagnostic use Tomography, Emission-Computed, Single-Photon Ventricular Function, Left* |
| Chemical | |
Reg. No./Substance:
|
0/Thallium Radioisotopes |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Acetylcholine-induced vasoconstrictor response of coronary vessels in rats: a possible contribution ...
Next Document: Successful treatment of intraoperative pulmonary tumor embolism from renal cell carcinoma.