Document Detail


Effect of reaction temperature on the determination of rat serum IgE by the avidin-biotin method.
MedLine Citation:
PMID:  8987869     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We established an avidin-biotin method for the sensitive determination of rat IgE and found that a non-specific signal was generated depending on the reaction temperature. When the sera of rats immunized or not with ovalbumin (OVA) were fractionated in a hydroxyapatite column and OVA-specific IgE was determined by the avidin-biotin method at 4 degrees C or 37 degrees C, OVA-specific IgE peaks were detected at 37 degrees C, even with nonimmunized rats, but not at 4 degrees C.
Authors:
K Yamada; A Nakao; M Takasugi; Y Itoh; N A Hassan; M Sugano
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Bioscience, biotechnology, and biochemistry     Volume:  60     ISSN:  0916-8451     ISO Abbreviation:  Biosci. Biotechnol. Biochem.     Publication Date:  1996 Nov 
Date Detail:
Created Date:  1997-02-24     Completed Date:  1997-02-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9205717     Medline TA:  Biosci Biotechnol Biochem     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  1891-2     Citation Subset:  B    
Affiliation:
Department of Food Science and Technology, Faculty of Agriculture, Kyushu University, Fukuoka, Japan.
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MeSH Terms
Descriptor/Qualifier:
Animals
Avidin / chemistry
Biotin / chemistry
Enzyme-Linked Immunosorbent Assay
Hydroxyapatites
Immunoglobulin E / analysis*,  isolation & purification
Indicators and Reagents
Male
Ovalbumin / immunology
Rats
Rats, Inbred BN
Temperature
Chemical
Reg. No./Substance:
0/Hydroxyapatites; 0/Indicators and Reagents; 1405-69-2/Avidin; 37341-29-0/Immunoglobulin E; 58-85-5/Biotin; 9006-59-1/Ovalbumin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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