Document Detail


Effect of the rate of blood loss on the plasma catecholamine response.
MedLine Citation:
PMID:  4050459     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In the present experiments the influence on the sympatho-adrenal system of the rate of haemorrhage-induced blood pressure fall in dogs was studied by measuring the plasma catecholamine response. Bleeding to a mean arterial pressure of 5.3 kPa in either 10 or 40 minutes caused an identical increase in the plasma catecholamine level. Similarly, there was no difference in bleeding volumes between the two groups. Within these limits the magnitude of the early catecholamine response was independent of the rate of the haemorrhage-induced decrease of blood pressure. The magnitude of the sympatho-adrenal response depended on the amount of lost blood. Bleeding for 80 minutes to the same pressure resulted in a considerably larger loss of blood and higher plasma catecholamine levels. No relationship was, however, found between the extent of the catecholamine response and the amount of the bleeding volume, probably due to some interaction with other control mechanisms.
Authors:
K Tárnoky; S Nagy
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta physiologica Hungarica     Volume:  66     ISSN:  0231-424X     ISO Abbreviation:  Acta Physiol Hung     Publication Date:  1985  
Date Detail:
Created Date:  1985-11-12     Completed Date:  1985-11-12     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8309201     Medline TA:  Acta Physiol Hung     Country:  HUNGARY    
Other Details:
Languages:  eng     Pagination:  143-53     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adrenal Glands / innervation
Animals
Bleeding Time
Blood Pressure
Dogs
Epinephrine / blood*
Hemodynamics
Hemorrhage / blood*
Norepinephrine / blood*
Sympathetic Nervous System / physiology
Time Factors
Chemical
Reg. No./Substance:
51-41-2/Norepinephrine; 51-43-4/Epinephrine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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