Document Detail

Effect of quercetin supplementation on maximal oxygen uptake in men and women.
MedLine Citation:
PMID:  20054739     Owner:  NLM     Status:  MEDLINE    
Quercetin is a naturally occurring flavonoid with anti-oxidant and anti-inflammatory properties. The effect of quercetin supplementation on maximal oxygen uptake (VO(2max)) is unknown. The purpose of this investigation was to test the effects of quercetin supplementation on VO(2max) in untrained, sedentary individuals. After baseline treadmill VO(2max) testing, 11 participants (5 males, 6 females) ingested either placebo or quercetin-supplemented (1000 mg x day(-1)) food bars in a randomized, double-blind, counterbalanced, crossover research design. The participants ingested food bars for six consecutive mornings (5 days). On the sixth morning, participants underwent repeat VO(2max) testing. After a 22 day wash-out, the participants repeated baseline VO(2max) testing, daily consumption of the opposite food bars, and post-supplementation VO(2max) testing. The condition x time interaction for VO(2max) was non-significant when expressed in absolute (litres x min(-1); P = 0.929) and relative (ml x kg(-1) x min(-1); P = 0.778) terms. These findings were similar when taking sex into account (P > 0.05). The mean difference in VO(2max) change from pre to post between groups (quercetin vs. placebo) was 0.139 ml x kg(-1) x min(-1) (P = 0.780). Other physiological measures also were similar between conditions (P > 0.05). In conclusion, 5 days of quercetin supplementation did not influence VO(2max) or related variables in sedentary men and women.
Matthew S Ganio; Lawrence E Armstrong; Evan C Johnson; Jennifer F Klau; Kevin D Ballard; Bozena Michniak-Kohn; Diksha Kaushik; Carl M Maresh
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Journal of sports sciences     Volume:  28     ISSN:  1466-447X     ISO Abbreviation:  J Sports Sci     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-04-14     Completed Date:  2010-08-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8405364     Medline TA:  J Sports Sci     Country:  England    
Other Details:
Languages:  eng     Pagination:  201-8     Citation Subset:  IM    
Human Performance Laboratory, University of Connecticut, Storrs, CT, USA.
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MeSH Terms
Antioxidants / pharmacology*
Cross-Over Studies
Dietary Supplements*
Double-Blind Method
Exercise / physiology*
Oxygen Consumption / drug effects*
Plant Extracts / pharmacology*
Quercetin / pharmacology*
Running / physiology
Walking / physiology
Young Adult
Reg. No./Substance:
0/Antioxidants; 0/Plant Extracts; 117-39-5/Quercetin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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