Document Detail

Effect of push enteroscopy on transfusion requirements and quality of life in patients with unexplained gastrointestinal bleeding.
MedLine Citation:
PMID:  9068462     Owner:  NLM     Status:  MEDLINE    
AIM: The aim of our study was to determine whether push enteroscopy altered transfusion requirements or quality of life in patients with unexplained gastrointestinal bleeding. METHODS: Twenty-nine patients with gastrointestinal bleeding unexplained by upper endoscopy and colonoscopy or persistent despite appropriate therapy after these procedures, underwent enteroscopy. Transfusion records in the year preceding and after the procedure were obtained from blood bank records and from telephone interviews every 6 months. RESULTS: Of 29 patients, 20 had received a transfusion (mean 8 +/- 3 units per patient) in the year preceding enteroscopy. In the year after the enteroscopy, 11 patients required transfusion (p = 0.034), and the mean transfusion requirement fell to 4 +/- 2 units, (p = 0.007). Angiodysplasia, the most frequent lesion found at enteroscopy (13 patients, 45%) were treated by endoscopic cautery. These patients had received an average of 13 +/- 6 units of packed cells per patient in the year preceding the procedure. In the year after enteroscopy, there was a significant reduction in transfusions (6 +/- 3 units per patient; p = 0.021). Of the 13 patients, 4 (31%) no longer required transfusions. Median functional status improved from 60 to 90 (p = 0.005). CONCLUSIONS: Enteroscopy alters the outcome of some patients with obscure gastrointestinal bleeding by reducing or eliminating bleeding and improving functional status.
N Vakil; V Huilgol; I Khan
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American journal of gastroenterology     Volume:  92     ISSN:  0002-9270     ISO Abbreviation:  Am. J. Gastroenterol.     Publication Date:  1997 Mar 
Date Detail:
Created Date:  1997-04-08     Completed Date:  1997-04-08     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0421030     Medline TA:  Am J Gastroenterol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  425-8     Citation Subset:  IM    
University of Wisconsin Medical School, Milwaukee, USA.
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MeSH Terms
Angiodysplasia / diagnosis,  surgery
Blood Banks
Blood Transfusion*
Diagnostic Imaging
Endoscopy, Gastrointestinal*
Follow-Up Studies
Gastrointestinal Hemorrhage / diagnosis*,  psychology,  surgery,  therapy
Interviews as Topic
Intestinal Diseases / diagnosis,  surgery
Middle Aged
Quality of Life*
Treatment Outcome

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