Document Detail

Effect of pulmonary hypertension on lung compliance in newborn lambs.
MedLine Citation:
PMID:  3670907     Owner:  NLM     Status:  MEDLINE    
We studied the effects of increased pulmonary arterial pressure and vascular resistance on lung compliance in 12 anesthetized newborn lambs. Lung compliance was unaffected by large changes in pulmonary artery pressure and pulmonary vascular resistance (80% increase) that were induced by either hypoxia or acidosis. We conclude that contraction of the pulmonary vascular smooth muscle in normal newborn lambs does not affect the stiffness of the lung in the parenchymal regions undergoing volume change during ventilation.
A J Caeton; B W Goetzman; S H Bennett; J M Milstein
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Pediatric pulmonology     Volume:  3     ISSN:  8755-6863     ISO Abbreviation:  Pediatr. Pulmonol.     Publication Date:    1987 Sep-Oct
Date Detail:
Created Date:  1987-12-17     Completed Date:  1987-12-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8510590     Medline TA:  Pediatr Pulmonol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  324-7     Citation Subset:  IM    
Department of Pediatrics, School of Medicine, University of California, Davis 95616.
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MeSH Terms
Animals, Newborn*
Hypertension, Pulmonary / physiopathology*
Lung Compliance*
Vascular Resistance

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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