Document Detail

Effect of psychiatric group intervention on natural-killer cell activity and pregnancy rate.
MedLine Citation:
PMID:  12220802     Owner:  NLM     Status:  MEDLINE    
We investigated the effects of psychiatric group intervention on the emotions, natural-killer (NK) cell activity and pregnancy rate in Japanese infertile women by a randomized study. Thirty-seven women completed a 5-session intervention program and were compared with 37 controls. Psychological discomfort and NK-cell activity (47.7% to 34.1%, P<.0001) significantly decreased after the intervention, whereas no significant changes were observed in controls. According to a 1-year follow-up of both groups, the pregnancy rate in the intervention group was significantly higher than that of controls (37.8% vs. 13.5%, P=.03). Psychological group intervention was therefore effective in Japanese infertile women.
Takashi Hosaka; Hidehiko Matsubayashi; Yoko Sugiyama; Shun-ichiro Izumi; Tsunehisa Makino
Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  General hospital psychiatry     Volume:  24     ISSN:  0163-8343     ISO Abbreviation:  Gen Hosp Psychiatry     Publication Date:    2002 Sep-Oct
Date Detail:
Created Date:  2002-09-10     Completed Date:  2002-12-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7905527     Medline TA:  Gen Hosp Psychiatry     Country:  United States    
Other Details:
Languages:  eng     Pagination:  353-6     Citation Subset:  IM    
Department of Psychiatry and Behavioral Science, Tokai University School of Medicine, Kanagawa 259-1193, Japan.
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MeSH Terms
Infertility, Female / epidemiology,  immunology,  psychology
Killer Cells, Natural / immunology*
Mental Disorders / epidemiology,  immunology*,  therapy*
Pregnancy Rate*
Psychotherapy, Group / statistics & numerical data*
Treatment Outcome

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