| Effect of a protein meal in stomach and jejunum on gastric secretory response to pentagastrin in cats. | |
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MedLine Citation:
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PMID: 3928288 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A humoral gastrin potentiating mechanism was previously demonstrated in the upper intestine of cats. The present study was carried out on 10 cats with a gastric fistula (GF) and a Heidenhain pouch (HP). In five of the cats the duodenum and proximal jejunum were excluded as a Roux-en-Y loop, and the other cats were provided with an isolated jejunal Thirty-Vella loop. In the Roux-en-Y loop cats, a protein-rich oral meal augmented the maximal HP acid response to pentagastrin but not the pepsin response. Protein-rich food in the Thirty-Vella loop did not stimulate acid secretion, nor did it augment the maximal GF or HP acid response to pentagastrin. Previous and present results suggest that an unknown humoral gastrin-potentiating mechanism is activated by a protein-rich meal in the stomach and the duodenum but not in the jejunum. The mechanism potentiates pentagastrin-induced acid, but not pepsin, secretion. |
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Authors:
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M Fernström; S Emås |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Digestive diseases and sciences Volume: 30 ISSN: 0163-2116 ISO Abbreviation: Dig. Dis. Sci. Publication Date: 1985 Sep |
Date Detail:
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Created Date: 1985-10-04 Completed Date: 1985-10-04 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7902782 Medline TA: Dig Dis Sci Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 877-83 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cats Dietary Proteins / pharmacology* Enteral Nutrition Gastric Acid / secretion Gastric Mucosa / secretion* Gastrins / physiology Jejunum Pentagastrin / pharmacology* Pepsin A / metabolism |
| Chemical | |
Reg. No./Substance:
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0/Dietary Proteins; 0/Gastrins; 5534-95-2/Pentagastrin; EC 3.4.23.1/Pepsin A |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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