| Effect of prostaglandin synthesis inhibition on the central activity of noradrenaline in rats. | |
MedLine Citation:
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PMID: 7246205 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effects of paracetamol and indomethacin on the action of centrally administered noradrenaline (NA) on the blood pressure, heart rate and rectal body temperature were studied in rats. It was demonstrated that both these substances increased NA effect on the arterial blood pressure and heart rate but caused no changes in NA effect on body temperature. These results suggest a modulating action of prostaglandins in the central nervous system on the functions of the centres regulating cardiovascular functions. |
Authors:
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R Brus; Z S Herman; A Sokoła; B Zielińska |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta physiologica Polonica Volume: 32 ISSN: 0044-6033 ISO Abbreviation: Acta Physiol Pol Publication Date: 1981 Jan-Feb |
Date Detail:
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Created Date: 1981-08-27 Completed Date: 1981-08-27 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 2985166R Medline TA: Acta Physiol Pol Country: POLAND |
Other Details:
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Languages: eng Pagination: 47-51 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acetaminophen
/
pharmacology Animals Autonomic Nervous System / physiology* Blood Pressure Body Temperature Heart Rate Hemodynamics* Indomethacin / pharmacology Male Norepinephrine / pharmacology, physiology* Prostaglandin Antagonists / pharmacology Prostaglandins / physiology* Rats |
| Chemical | |
Reg. No./Substance:
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0/Prostaglandin Antagonists; 0/Prostaglandins; 103-90-2/Acetaminophen; 51-41-2/Norepinephrine; 53-86-1/Indomethacin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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