Document Detail

Effect of prolonged nifedipine or captopril therapy on lymphocyte magnesium and potassium levels in hypertension.
MedLine Citation:
PMID:  8402763     Owner:  NLM     Status:  MEDLINE    
The effect of prolonged treatment with calcium channel blockers on potassium and magnesium stores is uncertain. We measured lymphocyte and serum magnesium and potassium in 28 patients treated for hypertension for 6 months with nifedipine or captopril. There was no difference in serum or lymphocyte concentrations in the two groups compared to 45 healthy, normotensive controls. These results suggest that intracellular cation levels are maintained with prolonged therapy with calcium channel blockers.
F Lavin; S O'Keeffe; H Grimes; J Finn; A Mannion; K Daly
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Cardiology     Volume:  82     ISSN:  0008-6312     ISO Abbreviation:  Cardiology     Publication Date:  1993  
Date Detail:
Created Date:  1993-11-23     Completed Date:  1993-11-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  1266406     Medline TA:  Cardiology     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  405-8     Citation Subset:  IM    
Department of Cardiology, University College Hospital, Galway, Ireland.
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MeSH Terms
Captopril / administration & dosage*
Hypertension / blood,  drug therapy*
Lymphocytes / drug effects*,  metabolism
Magnesium / blood*
Middle Aged
Nifedipine / administration & dosage*
Potassium / blood*
Reg. No./Substance:
21829-25-4/Nifedipine; 62571-86-2/Captopril; 7439-95-4/Magnesium; 7440-09-7/Potassium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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