Document Detail


Effect of progesterone treatment due to threatened abortion in early pregnancy for obstetric and perinatal outcomes.
MedLine Citation:
PMID:  20079582     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Progesterone supplementation has been used in a large number of women with threatened abortion for decades, despite various degrees of success, and contradictory and ever-changing views about its efficacy. The majority of previous literature has mainly focused on evaluation the effect of progesterone on pregnancy outcome of threatened abortion. No controlled epidemiological studies of obstetric and perinatal outcomes, including preterm birth, pregnancy complications and low birth weight newborns, in pregnant women with progesterone treatment have been published. The data of 523 pregnant women with progesterone treatment in the second and third months of pregnancy due to threatened abortion was compared with the data of other 21,054 pregnant women in the Department of Obstetrics, West China Second University Hospital for a period of 6years from January 2002 to October 2008. There was no difference in mean gestational age at delivery and birth weight, in addition the rate of preterm birth, pregnancy complications and low birth weight newborns. Intramuscular progesterone treatment due to threatened abortion during early pregnancy did not associate with a higher risk for pregnancy complications, preterm birth and low birth weight newborns.
Authors:
Lijun Duan; Denglu Yan; Weiyue Zeng; Xiao Yang; Qiang Wei
Publication Detail:
Type:  Journal Article     Date:  2010-01-15
Journal Detail:
Title:  Early human development     Volume:  86     ISSN:  1872-6232     ISO Abbreviation:  Early Hum. Dev.     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-02-17     Completed Date:  2010-05-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7708381     Medline TA:  Early Hum Dev     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  41-3     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Sichuan, 610041, PR China.
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MeSH Terms
Descriptor/Qualifier:
Abortion, Threatened / drug therapy*
Adult
Female
Humans
Patient Selection
Pregnancy
Pregnancy Complications
Pregnancy Outcome
Progesterone / administration & dosage,  adverse effects*
Retrospective Studies
Treatment Outcome
Chemical
Reg. No./Substance:
57-83-0/Progesterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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