| Effect of progesterone alone and in combination with either corticosterone, 17 beta-estradiol or insulin on prolactin-stimulated fatty acid synthesis in mammary explants from pseudopregnant rabbits. | |
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MedLine Citation:
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PMID: 6391451 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Progesterone up to 15.9 mumol/l progressively suppressed prolactin-stimulated fatty acid synthesis in cultured mammary explants from 11-day pseudopregnant rabbits, but did not influence the proportion of fatty acids of medium chain length (C8:0-C12:0). Greater sensitivity to progesterone inhibition was observed at the low end of the ranges of corticosterone (29 nmol/l) and insulin (4.2 nmol/l) concentrations in the culture medium, which suggests an interaction between the hormones. A range of from 0.0001 to 10 mumol/l of 17 beta-estradiol concentrations had no effect on prolactin-stimulated fatty acid synthesis in the presence or absence of progesterone. |
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Authors:
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P Martyn; I R Falconer |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Australian journal of biological sciences Volume: 37 ISSN: 0004-9417 ISO Abbreviation: Aust. J. Biol. Sci. Publication Date: 1984 |
Date Detail:
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Created Date: 1985-01-18 Completed Date: 1985-01-18 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370613 Medline TA: Aust J Biol Sci Country: AUSTRALIA |
Other Details:
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Languages: eng Pagination: 79-84 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Corticosterone / pharmacology* Culture Techniques Estradiol / pharmacology* Fatty Acids / biosynthesis* Female Insulin / pharmacology* Lactates / metabolism Lactic Acid Mammary Glands, Animal / metabolism* Progesterone / pharmacology* Prolactin / pharmacology* Pseudopregnancy / metabolism* Rabbits |
| Chemical | |
Reg. No./Substance:
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0/Fatty Acids; 0/Lactates; 11061-68-0/Insulin; 50-21-5/Lactic Acid; 50-22-6/Corticosterone; 50-28-2/Estradiol; 57-83-0/Progesterone; 9002-62-4/Prolactin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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