Document Detail

Effect of probiotics on intestinal barrier function.
MedLine Citation:
PMID:  19538305     Owner:  NLM     Status:  MEDLINE    
Impairment of the intestinal barrier is a key event in various gastrointestinal diseases, including inflammatory bowel diseases, celiac disease, gastrointestinal infections, diarrhea, and critical illness. Recent studies demonstrated that probiotic bacteria have beneficial effects in these diseases by effectively improving intestinal barrier function. This article reviews available data on the effect of probiotics on intestinal barrier function in vitro, in animal models, and in clinical studies.
Rudolf Mennigen; Matthias Bruewer
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Annals of the New York Academy of Sciences     Volume:  1165     ISSN:  1749-6632     ISO Abbreviation:  Ann. N. Y. Acad. Sci.     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-06-22     Completed Date:  2009-08-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7506858     Medline TA:  Ann N Y Acad Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  183-9     Citation Subset:  IM    
Department of General and Visceral Surgery, University Hospital Muenster, Muenster, Germany.
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MeSH Terms
Enteropathogenic Escherichia coli / pathogenicity
Inflammatory Bowel Diseases / immunology,  therapy*
Intestines / cytology,  immunology,  metabolism*,  microbiology*
Probiotics / therapeutic use*

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