Document Detail

Effect of a probiotic multivitamin compound on stress and exhaustion.
MedLine Citation:
PMID:  12201355     Owner:  NLM     Status:  MEDLINE    
This 6-month study evaluated a probiotic multivitamin preparation in 42 adult men and women suffering from stress or exhaustion. The preparation was taken daily with breakfast. A psychological-neurologic questionnaire assessed psycho-organic, central vegetative, and somatic discomforts, and a validated list of adjectives was used to indicate the effect of therapy. At the end of the study, an overall 40.7% improvement in stress was noted, representing significant improvements of 17.4% in positive conditions and of 23.3% in negative conditions (both P<.001). In addition, decreases of 29% in the frequency of infections and of 91% in gastrointestinal discomforts, both established indicators of stress, were recorded. The preparation was well tolerated. This probiotic multivitamin is suitable for reducing stress or exhaustion, or both, as well as for improving the immune system, specifically gastrointestinal health.
Joerg Gruenwald; Hans-Joachim Graubaum; Andrea Harde
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Advances in therapy     Volume:  19     ISSN:  0741-238X     ISO Abbreviation:  Adv Ther     Publication Date:    2002 May-Jun
Date Detail:
Created Date:  2002-08-30     Completed Date:  2002-09-13     Revised Date:  2006-04-13    
Medline Journal Info:
Nlm Unique ID:  8611864     Medline TA:  Adv Ther     Country:  United States    
Other Details:
Languages:  eng     Pagination:  141-50     Citation Subset:  T    
PhytoPharm Consulting, Berlin, Germany.
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MeSH Terms
Drug Combinations
Fatigue / drug therapy*
Middle Aged
Probiotics / administration & dosage*
Stress, Psychological / drug therapy*
Vitamins / administration & dosage*
Reg. No./Substance:
0/Drug Combinations; 0/Vitamins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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