| Effect of primary percutaneous coronary intervention on myocardial repolarization. | |
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MedLine Citation:
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PMID: 21941202 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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OBJECTIVE: We aimed to investigate the effect of coronary perfusion on QT interval dispersion in patients with acute myocardial infarction (MI). METHODS: Seventy-seven consecutive patients who had undergone primary percutaneous coronary intervention (PCI) for a first ST segment elevation MI during the first 12 h of symptom onset were included in the study. After achievement of thrombolysis in MI (TIMI) 3 flow of the infarct-related artery, corrected TIMI frame count (cTFC) and TIMI myocardial perfusion grade (TMPG) were measured. ECGs were performed in the following manner: at baseline, within 1 h after completion of the procedure, 24 h after the procedure and 48 h after the procedure. The corrected QT dispersion (QTd) and ST segment resolution (STR) were calculated. RESULTS: There was a difference between the durations of corrected QTd (cQTd) before PCI and cQTd just after PCI. On the first day, cQTd before PCI was significantly more prolonged (52.3 ± 80 vs. 41.5 ± 49, P = 0.05) than cQTd on second day (52.3 ± 80 vs. 37 ± 50, P = 0.001). In the correlation analysis conducted among the durations of cQTd, cTFC and TMPG, no significant association was established. STR was, however, inversely correlated with duration of cQTd. CONCLUSION: Our study results demonstrated that primary percutaneous coronary intervention leads to progressive shortening of QT dispersion in successful reperfusion, even in reduced cTFC. |
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Authors:
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Emine Bilen; Ayşe S Yasar; Mehmet Bilge; Isa O Yuksel; Uğur Aslantas; Mustafa Kurt; Göktürk Ipek; Mehmet F Karakaş; Ibrahim H Tanboğa |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of cardiovascular medicine (Hagerstown, Md.) Volume: 12 ISSN: 1558-2035 ISO Abbreviation: J Cardiovasc Med (Hagerstown) Publication Date: 2011 Nov |
Date Detail:
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Created Date: 2011-09-29 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101259752 Medline TA: J Cardiovasc Med (Hagerstown) Country: United States |
Other Details:
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Languages: eng Pagination: 795-9 Citation Subset: IM |
Affiliation:
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aDepartment of Cardiology, Ataturk Education and Research Hospital, Ankara bDepartment of Cardiology, Erzurum Education and Research Hospital, Erzurum, Turkey. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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