Document Detail

Effect of primary percutaneous coronary intervention on myocardial repolarization.
MedLine Citation:
PMID:  21941202     Owner:  NLM     Status:  In-Data-Review    
OBJECTIVE: We aimed to investigate the effect of coronary perfusion on QT interval dispersion in patients with acute myocardial infarction (MI).
METHODS: Seventy-seven consecutive patients who had undergone primary percutaneous coronary intervention (PCI) for a first ST segment elevation MI during the first 12 h of symptom onset were included in the study. After achievement of thrombolysis in MI (TIMI) 3 flow of the infarct-related artery, corrected TIMI frame count (cTFC) and TIMI myocardial perfusion grade (TMPG) were measured. ECGs were performed in the following manner: at baseline, within 1 h after completion of the procedure, 24 h after the procedure and 48 h after the procedure. The corrected QT dispersion (QTd) and ST segment resolution (STR) were calculated.
RESULTS: There was a difference between the durations of corrected QTd (cQTd) before PCI and cQTd just after PCI. On the first day, cQTd before PCI was significantly more prolonged (52.3 ± 80 vs. 41.5 ± 49, P = 0.05) than cQTd on second day (52.3 ± 80 vs. 37 ± 50, P = 0.001). In the correlation analysis conducted among the durations of cQTd, cTFC and TMPG, no significant association was established. STR was, however, inversely correlated with duration of cQTd.
CONCLUSION: Our study results demonstrated that primary percutaneous coronary intervention leads to progressive shortening of QT dispersion in successful reperfusion, even in reduced cTFC.
Emine Bilen; Ayşe S Yasar; Mehmet Bilge; Isa O Yuksel; Uğur Aslantas; Mustafa Kurt; Göktürk Ipek; Mehmet F Karakaş; Ibrahim H Tanboğa
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of cardiovascular medicine (Hagerstown, Md.)     Volume:  12     ISSN:  1558-2035     ISO Abbreviation:  J Cardiovasc Med (Hagerstown)     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-09-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101259752     Medline TA:  J Cardiovasc Med (Hagerstown)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  795-9     Citation Subset:  IM    
aDepartment of Cardiology, Ataturk Education and Research Hospital, Ankara bDepartment of Cardiology, Erzurum Education and Research Hospital, Erzurum, Turkey.
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