| Effect of pretransplantation hemoglobin blood concentration on renal allograft survival and function. | |
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MedLine Citation:
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PMID: 20430165 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effect of pretransplantation hemoglobin (Hb) concentration on the outcome of kidney transplantation (KTx) was studied in 188 adult kidney transplant recipients. Patients were divided into 2 groups: high Hb (>or=10 g/dL; n=97) and low Hb (<10 g/dL; n=91). Both groups were matched for recipient sex, donor age and sex, donor-recipient blood groups, indications for kidney transplantation, and degree of sensitization. Acute rejection episodes occurred in 20 patients in the high-Hb group (20.6%) and 18 in the low-Hb group (19.8%). Antithymocyte globulin-Fresenius therapy was required in 6 patients in the high-Hb group compared with 5 patients in the low-Hb group. Infection rate, 1-year actuarial patient and graft survival, incidence of delayed and slow graft function, and number of surgical complications were comparable between groups. Compared with the low Hb group, in the high-Hb group, hospital stay was longer, creatinine concentration at 12 months post-KTx and serum glucose concentration at 6 months post-KTx were significantly higher, and pre- and posttransplantation Hb concentrations were higher. The need for post-KTx transfusions was comparable between groups. Pretransplantation Hb concentration did not affect outcome except for longer initial hospital stay and 1-year creatinine concentration. |
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Authors:
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M M Abou-Jaoude; N Nawfal; R Najm; M Honeidi; J Shaheen; W Y Almawi |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Transplantation proceedings Volume: 42 ISSN: 1873-2623 ISO Abbreviation: Transplant. Proc. Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-04-30 Completed Date: 2010-08-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0243532 Medline TA: Transplant Proc Country: United States |
Other Details:
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Languages: eng Pagination: 760-2 Citation Subset: IM |
Copyright Information:
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Copyright (c) 2010 Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Surgery, Sacré-Coeur Hospital, Baabda-Hazmieh, Beirut, Lebanon. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antibodies, Monoclonal / therapeutic use Antilymphocyte Serum / therapeutic use Blood Glucose / analysis Blood Group Antigens / metabolism Creatinine / blood Female Graft Rejection / epidemiology Graft Survival Hemoglobinometry Hemoglobins / metabolism* Humans Immunoglobulin G / therapeutic use Immunosuppressive Agents / therapeutic use Kidney Transplantation / immunology, physiology* Male Postoperative Complications / epidemiology Postoperative Period Preoperative Period Retrospective Studies Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Monoclonal; 0/Antilymphocyte Serum; 0/Blood Glucose; 0/Blood Group Antigens; 0/Hemoglobins; 0/Immunoglobulin G; 0/Immunosuppressive Agents; 152923-56-3/daclizumab; 60-27-5/Creatinine |
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