Document Detail

Effect of preoperative feeding on gastric emptying following spinal anesthesia: a randomized controlled trial.
MedLine Citation:
PMID:  20177860     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Preoperative fasting is associated with various untoward postoperative health problems. Previous studies have stressed the advantages of preoperative feeding with a carbohydrate-rich drink 2 hours before surgery; this protocol does not increase the risk of gastric-content aspiration but reduces the level of anxiety and thirstiness during the perioperative period. Spinal anesthesia with the local anesthetic bupivacaine can decrease gastric emptying in the early postoperative period. However, the effect of spinal anesthesia on the gastric emptying rate following preoperative feeding is unknown. The aim of this study was to determine the impact of preoperative feeding with a clear carbohydrate-rich drink on gastric emptying early after orthopedic surgery under spinal anesthesia. METHODS: A total of 110 patients scheduled for semi-elective orthopedic surgery under spinal anesthesia were included in a randomized controlled trial. Patients were randomly assigned to two groups: group 1 (56 patients) received a standardized 200 ml of clear carbohydrate-enriched drink orally 2 hours before surgery; group 2 (54 patients) acted as a control group with no preoperative feeding. Gastric emptying was evaluated with a paracetamol test at five time points: 15 min, 30 min, 60 min, 90 min and 120 min after administration of paracetamol. RESULTS: No significant differences were observed between the two groups in paracetamol plasma concentrations or area under the curve during the early postoperative period. CONCLUSION: In patients undergoing spinal anesthesia, preoperative feeding 2 hours before surgery had no influence on the gastric emptying rate, indicating that preoperative feeding does not increase the risk of gastric-content aspiration and can be given safely.
Alen Protic; Dean Turina; Dubravka Matani?; Josip Spanjol; Marta Zuvic-Butorac; Alan Sustic
Publication Detail:
Type:  Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Wiener klinische Wochenschrift     Volume:  122     ISSN:  1613-7671     ISO Abbreviation:  Wien. Klin. Wochenschr.     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-02-23     Completed Date:  2010-05-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  21620870R     Medline TA:  Wien Klin Wochenschr     Country:  Austria    
Other Details:
Languages:  eng     Pagination:  50-3     Citation Subset:  IM    
Department of Anesthesiology and ICU, University Hospital Rijeka, Rijeka, Croatia.
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MeSH Terms
Aged, 80 and over
Anesthesia, Spinal / methods*
Anesthetics, General / administration & dosage*
Gastric Emptying / drug effects*
Middle Aged
Preoperative Care / methods*
Reg. No./Substance:
0/Anesthetics, General

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