Document Detail

Effect of preload reduction on sonographic myocardial integrated backscatter.
MedLine Citation:
PMID:  18088055     Owner:  NLM     Status:  MEDLINE    
PURPOSE: Sonographic myocardial tissue characterization with integrated backscatter (IBS) is affected by both structural and functional properties of the myocardium. The aim of the present study was to investigate the effect of preload reduction by hemodialysis (HD) on IBS measurements. METHODS: Fifty-two patients on maintenance HD underwent echocardiography before and after a routine HD session. Measurements included the variation of IBS during the cardiac cycle (CV-IBS) and calibrated IBS (cal-IBS). RESULTS: After HD, there were significant reductions in left ventricular end-diastolic and end-systolic dimensions and left atrial diameter. There was a reduction in stroke volume and LV ejection fraction consistent with a reduction in preload. Furthermore, CV-IBS was significantly lower after HD (7.9 +/- 2.2 versus 6.9 +/- 1.8 dB, 7.0 +/- 2.1 versus 6.2 +/- 1.9 dB, and 9.0 +/- 2.6 versus 8.1 +/- 2.0 dB [p < 0.01], respectively, in the left anterior, lateral, and inferior wall of the ventricle). Cal-IBS remained unchanged after dialysis compared with baseline. CV-IBS and ultrafiltration volume were significantly correlated. CONCLUSION: HD leads to a decrease in CV-IBS that appears to be preload-dependent. This finding is in concordance with diminished left ventricular performance during HD.
Andrzej Minczykowski; Danuta Zaremba-Drobnik; Irena Pietrzak; Stanislaw Czekalski; Henryk Wysocki
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of clinical ultrasound : JCU     Volume:  36     ISSN:  0091-2751     ISO Abbreviation:  J Clin Ultrasound     Publication Date:    2008 Mar-Apr
Date Detail:
Created Date:  2008-03-10     Completed Date:  2008-07-31     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401663     Medline TA:  J Clin Ultrasound     Country:  United States    
Other Details:
Languages:  eng     Pagination:  157-65     Citation Subset:  IM    
Copyright Information:
(Copyright) 2007 Wiley Periodicals, Inc.
Department of Cardiology-Intensive Therapy, Poznan University of Medical Sciences, Przybyszewskiego 49, 60-355 Poznan, Poland.
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MeSH Terms
Blood Flow Velocity
Blood Volume
Echocardiography, Doppler / methods*
Image Processing, Computer-Assisted
Kidney Failure, Chronic / therapy
Observer Variation
Renal Dialysis
Reproducibility of Results
Stroke Volume
Ventricular Dysfunction, Left / physiopathology,  ultrasonography*
Ventricular Function, Left

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