Document Detail


Effect of pregnancy of cellular inflammation.
MedLine Citation:
PMID:  7150504     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Pregnancy inhibits macrophage accumulation within the peritoneal cavity of Wistar rats when inflammation is induced by phytohaemagglutinin (PHA). The inhibition of macrophages was considerably greater than that of polymorphonuclear leucocytes (PMNs) induced by sodium caseinate. Pregnancy did not significantly alter macrophage accumulation to PHA injected into the pleural space or to nitrocellulose filters placed s.c. Cell-free homogenates prepared from the products of conception, but not normal liver, contained an anti-flammatory factor which, when injected i.v., inhibited macrophage accumulation to peritoneal but not to pleural or s.c. irritants. The responsible anti-inflammatory factor was identified as a peptide of mol. wt less than 1000.
Authors:
S J Normann; M Schardt; E Sorkin
Related Documents :
22605664 - Lateral ventricles in aneuploidies at 11-13 weeks' gestation.
6377924 - Mechanism of decreased pressor responsiveness to ang ii, ne, and vasopressin in pregnan...
25414264 - Maternal titers after adequate syphilotherapy during pregnancy.
6426044 - Comparative safety and efficacy of auranofin and parenteral gold compounds: a review.
8513614 - The predictive significance of clinical measures of brain injury in the newborn.
16437524 - Preimplantation genetic screening for abnormal number of chromosomes (aneuploidies) in ...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  British journal of experimental pathology     Volume:  63     ISSN:  0007-1021     ISO Abbreviation:  Br J Exp Pathol     Publication Date:  1982 Aug 
Date Detail:
Created Date:  1983-03-24     Completed Date:  1983-03-24     Revised Date:  2012-05-07    
Medline Journal Info:
Nlm Unique ID:  0372543     Medline TA:  Br J Exp Pathol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  432-7     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Ascitic Fluid / cytology
Cell-Free System
Embryo, Mammalian
Female
Leukocytes / drug effects
Macrophage Activation
Macrophages / drug effects*
Peritoneal Cavity / pathology
Peritonitis / chemically induced,  prevention & control*
Phytohemagglutinins / pharmacology*
Pregnancy*
Rats
Grant Support
ID/Acronym/Agency:
CA 22517-05/CA/NCI NIH HHS
Chemical
Reg. No./Substance:
0/Phytohemagglutinins
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Ultrastructure of the lung after ventilation.
Next Document:  The effect of accelerated release of rat neutrophil polymorphonuclear leucocytes from bone marrow on...