Document Detail

Effect of potential remineralizing agents on acid softened enamel.
MedLine Citation:
PMID:  21874937     Owner:  NLM     Status:  In-Process    
PURPOSE: To assess whether pastes containing casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and calcium sodium phosphosilicate (CSP) protect acid softened enamel against further erosive episodes.
METHODS: Enamel slabs of bovine teeth with preformed erosion-like lesions were randomly assigned to five treatment groups (n = 15): A) CPP-ACP (MI Paste, GC America); B) CPP-ACP+Fluoride (CPP-ACP+F, MI Plus Paste, GC America); C) CSP (Tooth Revitalizing Paste, Oravive); D) fluoridated dentifrice (FD, Sensodyne Cool Gel, GSK); E) control (CO, unexposed to any product). Paste treatments (1:3 slurry in deionized water or undiluted product in the case of the CPP-ACP formulae) were performed between five cycles of alternating erosive challenge (0.3% citric acid, pH = 3.2) and remineralization in artificial saliva. Specimens were analyzed by Knoop surface microhardness (SMH).
RESULTS: ANOVA indicated a significant (P< 0.0001) difference among the SMH values attained by acid softened enamel following the exposure to the pastes interspersed with erosion-remineralization cycles. Tukey's test ascertained that SMH values observed for the CPP-ACP+F and CSP groups did not differ from that of FD group, which were significantly higher than that found for the CO group. Specimens treated with CPP-ACP did not differ from any of the other groups.
Cecilia P Turssi; Fernando A Maeda; Danielle C F Messias; Francisco C Rehder Neto; Mônica C Serra; Daniel Galafassi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of dentistry     Volume:  24     ISSN:  0894-8275     ISO Abbreviation:  Am J Dent     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-08-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8806701     Medline TA:  Am J Dent     Country:  United States    
Other Details:
Languages:  eng     Pagination:  165-8     Citation Subset:  D    
Instituto e Centro de Pesquisas São Leopoldo Mandic, Laboratório de Ensaio de Materiais, SP, Brazil.
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