| Effect of positive-end expiratory pressure on accuracy of thermal-dye measurements of lung water. | |
| | |
MedLine Citation:
|
PMID: 3884898 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The thermal-dye indicator dilution technique of measuring extravascular lung water (EVLW-TD) correlates well with gravimetric measurement of lung water (EVLW-GR) when no positive-end expiratory pressure (PEEP) is used in both normal and edematous lungs. PEEP is often used to raise arterial oxygen tension in acute respiratory failure. This study was designed to answer the question: Does PEEP have an effect on the accuracy of the EVLW measurement by thermal dye? Sixteen mongrel dogs were anesthetized and intubated. Arterial and PA catheters were placed. They were divided into three groups and ventilated at PEEP levels of 5, 10, or 15 cm H2O. Fluids were given to minimize decrease in cardiac output with institution of PEEP. They were maintained for 5 hr with measurement of vital signs made hourly and measurement of blood gases and EVLW-TD made at baseline, 1, 3, and 5 hr. After final measurements, gravimetric determination of EVLW was done. Correlation between EVLWTD and EVLWGR remained good when low levels of PEEP were used. At 5 cm H2O PEEP, EVLWTD was 7.5 +/- 0.9 and EVLWGR was 5.4 +/- .3. At 10 cm H2O PEEP, they were 10.0 +/- 0.9 and 6.5 +/- 0.3. The correlations were 0.87 and 0.97, respectively. However, at 15 cm H2O PEEP, EVLWTD was 11.4 +/- 1.3 and EVLWGR was 7.5 +/- 0.6, with a correlation of only 0.59. The correlation between the two techniques seems to break down with higher levels of PEEP in dogs with normal lungs. |
| | |
Authors:
|
B L Enderson; C Rice; G S Moss |
Related Documents
:
|
11684988 - Effects of inverse ratio ventilation versus positive end-expiratory pressure on gas exc... 12059898 - Effects of lung recruitment maneuver and positive end-expiratory pressure on lung volum... 12687028 - Effects of positive end-expiratory pressure on oscillated volume during high frequency ... 2231798 - Auto-peep in the multisystem injured patient: an elusive complication. 19856188 - Arterial distensibility is reduced in overweight pre- and early pubescent children. 19157898 - Percutaneous transluminal angioplasty balloon inflation with syringes: who needs an inf... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: The Journal of surgical research Volume: 38 ISSN: 0022-4804 ISO Abbreviation: J. Surg. Res. Publication Date: 1985 Mar |
Date Detail:
|
Created Date: 1985-04-29 Completed Date: 1985-04-29 Revised Date: 2003-11-14 |
Medline Journal Info:
|
Nlm Unique ID: 0376340 Medline TA: J Surg Res Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 224-30 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Cardiac Output Dogs Dye Dilution Technique Positive-Pressure Respiration* Pulmonary Edema / diagnosis*, physiopathology, therapy Pulmonary Wedge Pressure Thermodilution / methods |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Furosemide during sustained left atrial hypertension in functionally anephric dogs: intravascular an...
Next Document: Hydrolytic activities of human pancreatic phospholipase A2 and endotoxin-stimulated endogenous phosp...