Document Detail

Effect of polyunsaturated fatty acids of the alpha-linolenic series on the development of rat testicles.
MedLine Citation:
PMID:  593069     Owner:  NLM     Status:  MEDLINE    
The effect of 22:6 omega 3 acid provided by dietary fish oil on the development of germinal tissue of rat testes, fatty acid composition of lipids, and linoleic or alpha-linolenic acid delta 6 desaturation capacity was investigated. Results were compared to those obtained in animals fed methyl palmitate and sunflower seed oil (linoleate). At 7 and 9 weeks of age, development of germinal tissue of animals fed fish oil was normal. The fatty acid composition showed a decrease in 22:5 omega 6 acid content and an increase in 22:6 omega 3 acid in triacylglycerol, phosphatidylcholine, and phosphatidylethanolamine. The fatty acid delta 6 desaturation capacity of testicules microsomes was increased. It is suggested that 22:6 omega 3 acid may functionally replace 22:5 omega 6 acid in germinal tissue.
S Ayala; R R Brenner; C G Dumm
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Lipids     Volume:  12     ISSN:  0024-4201     ISO Abbreviation:  Lipids     Publication Date:  1977 Dec 
Date Detail:
Created Date:  1978-02-18     Completed Date:  1978-02-18     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0060450     Medline TA:  Lipids     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1017-24     Citation Subset:  IM    
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MeSH Terms
Dietary Fats / metabolism*
Fatty Acids / metabolism
Linolenic Acids / pharmacology*
Testis / anatomy & histology,  growth & development*,  metabolism
Reg. No./Substance:
0/Dietary Fats; 0/Fatty Acids; 0/Linolenic Acids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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