Document Detail


Effect of picrotoxin-induced seizures on lipid composition of cortical tissue homogenate and its nuclear fraction in rats.
MedLine Citation:
PMID:  11177266     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The content of lipids in rat cortical tissue homogenate and fraction of neuronal nuclei was determined under normal conditions and after picrotoxin-induced seizures. Changes in lipid composition of homogenate and nuclear fraction differed considerably. In homogenate, the content of sphingomyelin, lysophosphatidylcholine, and total phospholipids increased, while the content of free fatty acid remained unchanged; in the nuclear fraction the total phospholipid content decreased, while the concentration of free fatty acids increased.
Authors:
T P Kulagina; I K Kolomiitseva; V I Arkhipov
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Bulletin of experimental biology and medicine     Volume:  130     ISSN:  0007-4888     ISO Abbreviation:  Bull. Exp. Biol. Med.     Publication Date:  2000 Sep 
Date Detail:
Created Date:  2001-02-22     Completed Date:  2001-05-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372557     Medline TA:  Bull Exp Biol Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  864-6     Citation Subset:  IM    
Affiliation:
Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino.
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MeSH Terms
Descriptor/Qualifier:
Animals
Cell Nucleus / metabolism
Cerebral Cortex / metabolism*,  physiopathology
Convulsants
Lipid Metabolism*
Male
Picrotoxin
Rats
Rats, Wistar
Seizures / chemically induced
Chemical
Reg. No./Substance:
0/Convulsants; 124-87-8/Picrotoxin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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