Document Detail

Effect of physical training on leukocyte rheology throughout induced ischaemia.
MedLine Citation:
PMID:  2129206     Owner:  NLM     Status:  MEDLINE    
Before and after a physical training programme a treadmill exercise was used to stress leg circulation and induce ischaemia in 20 patients affected by peripheral arterial occlusive disease (PAOD). Transcutaneous oxygen pressure (TcPO2) was monitored constantly and blood samples drawn at baseline, the onset of calf pain, the maximum walking time, the minimum TcPO2 value, and when the TcPO2 recovered half its basal value. The mononuclear and polymorphonuclear leucocyte subfractions were separated by density and their filterability rates (through 5 microns pore diameter Nuclepore filters) measured using a positive pressure filtration system. The mononuclear filterability rate was significantly impaired throughout the ischaemic event and inversely correlated with the TcPO2 values. Physical training while delaying the onset and progress of ischaemia did not modify this pattern, implying that regular exercise does not affect the rheological properties of leukocytes--impairments in which are markers of ischaemia.
G Ciuffetti; E Mannarino; M Mercuri; L Pasqualini; R Lombardini; C Ott; L Santambrogio
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International angiology : a journal of the International Union of Angiology     Volume:  9     ISSN:  0392-9590     ISO Abbreviation:  Int Angiol     Publication Date:    1990 Oct-Dec
Date Detail:
Created Date:  1991-08-13     Completed Date:  1991-08-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8402693     Medline TA:  Int Angiol     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  246-50     Citation Subset:  IM    
2nd Department of Internal Medicine, University of Perugia, Italy.
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MeSH Terms
Carbon Dioxide / blood
Intermittent Claudication / blood*,  physiopathology*
Ischemia / blood*,  physiopathology*
Leg / blood supply
Leukocytes, Mononuclear / physiology
Middle Aged
Monitoring, Physiologic
Neutrophils / physiology
Oxygen / blood
Physical Education and Training*
Reg. No./Substance:
124-38-9/Carbon Dioxide; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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