| Effect of physical training on leukocyte rheology throughout induced ischaemia. | |
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MedLine Citation:
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PMID: 2129206 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Before and after a physical training programme a treadmill exercise was used to stress leg circulation and induce ischaemia in 20 patients affected by peripheral arterial occlusive disease (PAOD). Transcutaneous oxygen pressure (TcPO2) was monitored constantly and blood samples drawn at baseline, the onset of calf pain, the maximum walking time, the minimum TcPO2 value, and when the TcPO2 recovered half its basal value. The mononuclear and polymorphonuclear leucocyte subfractions were separated by density and their filterability rates (through 5 microns pore diameter Nuclepore filters) measured using a positive pressure filtration system. The mononuclear filterability rate was significantly impaired throughout the ischaemic event and inversely correlated with the TcPO2 values. Physical training while delaying the onset and progress of ischaemia did not modify this pattern, implying that regular exercise does not affect the rheological properties of leukocytes--impairments in which are markers of ischaemia. |
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Authors:
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G Ciuffetti; E Mannarino; M Mercuri; L Pasqualini; R Lombardini; C Ott; L Santambrogio |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: International angiology : a journal of the International Union of Angiology Volume: 9 ISSN: 0392-9590 ISO Abbreviation: Int Angiol Publication Date: 1990 Oct-Dec |
Date Detail:
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Created Date: 1991-08-13 Completed Date: 1991-08-13 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8402693 Medline TA: Int Angiol Country: ITALY |
Other Details:
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Languages: eng Pagination: 246-50 Citation Subset: IM |
Affiliation:
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2nd Department of Internal Medicine, University of Perugia, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Carbon Dioxide
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blood Humans Intermittent Claudication / blood*, physiopathology* Ischemia / blood*, physiopathology* Leg / blood supply Leukocytes, Mononuclear / physiology Male Middle Aged Monitoring, Physiologic Neutrophils / physiology Oxygen / blood Physical Education and Training* Rheology |
| Chemical | |
Reg. No./Substance:
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124-38-9/Carbon Dioxide; 7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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