Document Detail


Effect of physical training on exercise capacity and gas exchange in patients with chronic heart failure.
MedLine Citation:
PMID:  8874256     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Decreased exercise capacity is the main factor restricting the daily life of patients with chronic congestive heart failure (CHF). We performed a controlled, randomized study to evaluate the effect of dynamic exercise training of moderate intensity on exercise capacity and gas exchange in patients with CHF. Twenty-seven patients with stable CHF, New York Heart Association (NYHA) functional class II and III, were randomized to training (n = 12) and control (n = 15) groups. During a 3-month period, the training group underwent a supervised physical training program using a bicycle ergometer for 30 min 3 times a week at a load corresponding to 50 to 60% of their peak oxygen consumption. Thereafter, they were advised to continue training at home for the next 3 months. The control group did not change their previous physical activity. A graded maximal exercise test with respiratory gas analysis and an endurance test with constant submaximal workload were performed at baseline and after 3 and 6 months. The exercise endurance increased from 14.7 +/- 2.0 to 27.8 +/- 2.7 min (p < 0.01) and the peak oxygen consumption tended to improve from 19.3 +/- 1.6 to 21.7 +/- 2.3 mL/kg/min (p = 0.09) during the supervised training period. At submaximal workloads, minute ventilation was reduced by 16% per se (p < 0.01) and by 7% in proportion to carbon dioxide production (p < 0.05). Oxygen consumption at the anaerobic threshold increased from 10.5 +/- 0.8 to 12.7 +/- 1.0 mL/kg/min (p < 0.05). The positive training effects were associated with an improvement in the NYHA functional class. The effects of supervised training were preserved during the home-based training period. The results indicate that physical training of moderate intensity significantly improves the exercise capacity and reduces the exaggerated ventilatory response to exercise, particularly at submaximal working levels in patients with CHF. This is associated with alleviation of symptoms.
Authors:
K Kiilavuori; A Sovijärvi; H Näveri; T Ikonen; H Leinonen
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Chest     Volume:  110     ISSN:  0012-3692     ISO Abbreviation:  Chest     Publication Date:  1996 Oct 
Date Detail:
Created Date:  1996-11-20     Completed Date:  1996-11-20     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  985-91     Citation Subset:  AIM; IM; S    
Affiliation:
Department of Medicine, Helsinki University Central Hospital, Finland.
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MeSH Terms
Descriptor/Qualifier:
Exercise / physiology*
Exercise Tolerance*
Female
Heart Failure / physiopathology*
Hemodynamics
Humans
Male
Middle Aged
Oxygen Consumption
Prospective Studies
Pulmonary Gas Exchange*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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