| Effect of phosphatidylcholine, lysophosphatidylcholine, arachidonic acid and docosahexaenoic acid on the motility of human sperm. | |
| | |
MedLine Citation:
|
PMID: 2947864 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Lysophosphatidylcholine, arachidonic acid and docosahexaenoic acid were found to have a concentration-dependent inhibitory effect on the motility of human sperm, whilst phosphatidylcholine had no effect. Seminal plasma attenuated the sperm-immobilizing potencies of these lipids. Because all of the three inhibitors of motility are hydrolytic products of phosphatidylcholine, and the catalytic enzyme, phospholipase A2, is known to be calcium dependent, it is suggested that calcium might inhibit sperm motility by activating phospholipase A2 which in turn releases lysophosphatidylcholine and free fatty acids. |
| | |
Authors:
|
C Y Hong; C C Shieh; P Wu; J J Huang; B N Chiang |
Related Documents
:
|
2123404 - Subcellular distribution of fatty acids, phospholipids and phospholipase a2 in human ne... 10212204 - Phospholipid-assisted refolding of an integral membrane protein. minimum structural fea... 5554104 - The apparent transfer of fatty acid from phosphatidylcholine to phosphatidylethanolamin... 2387334 - Unique molecular species composition of glycerolipids of frog rod outer segments. 17123874 - Quantification of free and total sialic acid excretion by lc-ms/ms. 2123404 - Subcellular distribution of fatty acids, phospholipids and phospholipase a2 in human ne... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: International journal of andrology Volume: 9 ISSN: 0105-6263 ISO Abbreviation: Int. J. Androl. Publication Date: 1986 Apr |
Date Detail:
|
Created Date: 1987-02-13 Completed Date: 1987-02-13 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8000141 Medline TA: Int J Androl Country: DENMARK |
Other Details:
|
Languages: eng Pagination: 118-22 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Arachidonic Acids
/
pharmacology* Docosahexaenoic Acids Fatty Acids, Unsaturated / pharmacology* Humans Lysophosphatidylcholines / pharmacology* Male Phosphatidylcholines / pharmacology* Sperm Motility / drug effects* |
| Chemical | |
Reg. No./Substance:
|
0/Arachidonic Acids; 0/Fatty Acids, Unsaturated; 0/Lysophosphatidylcholines; 0/Phosphatidylcholines; 25167-62-8/Docosahexaenoic Acids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Induction of a macrophage-suppressive lymphokine by soluble cryptococcal antigens and its associatio...
Next Document: EL-4 metastases in spleen and bone marrow suppress the NK activity generated in these organs.