| Effect of a casein/calcium phosphate-containing tooth cream and fluoride on enamel erosion in vitro. | |
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MedLine Citation:
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PMID: 16508274 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aim of this study was to determine whether a tooth cream containing casein/calcium phosphate (CasCP) protects enamel against erosion. Sixty bovine enamel specimens were prepared for profilometry and distributed into five groups. Specimens were rinsed with artificial saliva interrupted by 1% citric acid (pH 2.3) for 30 s 6 times daily for 14 days. Group 1 (n=12) was not treated (control); in group 2 (n=12) CasCP was applied for 120 s twice daily; in group 3 (n=12) 250 ppm fluoride as NaF was applied for 120 s twice daily; in group 4 (n=12) CasCP was applied for 120 s, then 250 ppm fluoride for 120 s twice daily, and in group 5 (n=12) amine fluoride (AmF) gel (12,500 ppm fluoride) was applied for 120 s twice daily. Differences between groups with respect to erosive enamel loss (profilometrically determined depth after 7 and 14 days) were tested by the Mann-Whitney test (alpha=0.05). After 7/14 days' erosive cycling, specimens treated with AmF gel showed significantly less enamel loss (18.5/35.5 microm; medians) than those treated with CasCP (25.5/46.9 microm), 250 ppm fluoride (25.0/ 40.9 microm), CasCP and 250 ppm fluoride (23.9/47.4 microm) or with no treatment (26.3/49.8 microm). It is concluded that highly fluoridated acidic AmF gel can protect enamel against erosion while CasCP, 250 ppm fluoride or a combination of CasCP and 250 ppm fluoride provide little protection. |
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Authors:
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A M Lennon; M Pfeffer; W Buchalla; K Becker; S Lennon; T Attin |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Caries research Volume: 40 ISSN: 0008-6568 ISO Abbreviation: Caries Res. Publication Date: 2006 |
Date Detail:
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Created Date: 2006-03-01 Completed Date: 2006-04-18 Revised Date: 2009-11-19 |
Medline Journal Info:
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Nlm Unique ID: 0103374 Medline TA: Caries Res Country: Switzerland |
Other Details:
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Languages: eng Pagination: 154-7 Citation Subset: D; IM |
Copyright Information:
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Copyright (c) 2006 S. Karger AG, Basel. |
Affiliation:
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Department of Operative Dentistry, Preventive Dentistry and Periodontology, University of Göttingen, Göttingen, Germany. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Amines
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administration & dosage Animals Ascorbic Acid / administration & dosage Calcium Phosphates / administration & dosage* Caseins / administration & dosage* Cattle Dental Enamel / drug effects Dental Enamel Solubility / drug effects Dentifrices / administration & dosage*, chemistry Diamines Dose-Response Relationship, Drug Drug Combinations Fluorides / administration & dosage Fluorides, Topical / administration & dosage* Hydrogen-Ion Concentration Sodium Fluoride / administration & dosage Statistics, Nonparametric Tin Fluorides / administration & dosage Tooth Erosion / chemically induced, prevention & control* |
| Chemical | |
Reg. No./Substance:
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0/Amines; 0/Calcium Phosphates; 0/Caseins; 0/Dentifrices; 0/Diamines; 0/Drug Combinations; 0/Fluorides; 0/Fluorides, Topical; 0/Olaflur; 0/Tin Fluorides; 10103-46-5/calcium phosphate; 37334-68-2/amine fluoride gel; 50-81-7/Ascorbic Acid; 7681-49-4/Sodium Fluoride |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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