| Effect of perfluorodecalin on the microsomal mono-oxygenase system in perfused rat livers. | |
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MedLine Citation:
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PMID: 6858199 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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1. An emulsion of perfluorodecalin was used as a substitute for erythrocytes in a synthetic medium in the perfusion of isolated rat livers. 2. The efficiency of this oxygen carrier in maintaining liver viability and function was compared with an erythrocyte-containing medium. 3. Activities of the microsomal mono-oxygenase system, secretion of bile and concn. of transaminases, potassium, glucose, urea, pO2 and pCO2 in the medium, and ATP and glycogen in the tissue, did not differ in the two experimental conditions. |
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Authors:
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A Guaitani; P Villa; I Bartosek |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Xenobiotica; the fate of foreign compounds in biological systems Volume: 13 ISSN: 0049-8254 ISO Abbreviation: Xenobiotica Publication Date: 1983 Jan |
Date Detail:
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Created Date: 1983-07-08 Completed Date: 1983-07-08 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 1306665 Medline TA: Xenobiotica Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 39-45 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenosine Triphosphate
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analysis Alanine Transaminase / analysis Animals Aspartate Aminotransferases / analysis Blood Substitutes / pharmacology* Fluorocarbons / pharmacology* Liver Glycogen / analysis Male Microsomes, Liver / drug effects, enzymology* Oxygen / blood Oxygenases / analysis* Perfusion Rats Rats, Inbred Strains |
| Chemical | |
Reg. No./Substance:
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0/Blood Substitutes; 0/Fluorocarbons; 0/Liver Glycogen; 306-94-5/perfluorodecalin; 56-65-5/Adenosine Triphosphate; 7782-44-7/Oxygen; EC 1.13.-/Oxygenases; EC 2.6.1.1/Aspartate Aminotransferases; EC 2.6.1.2/Alanine Transaminase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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