| Effect of pentobarbital on spectral characteristics and phase ratios of wave oscillations of cardiac contraction period and time of atrioventricular conduction in cats. | |
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MedLine Citation:
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PMID: 17073140 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Effects of pentobarbital on spectral characteristics and phase ratios of wave oscillations of the cardiac contraction period (RR interval) and time of atrioventricular conduction (AV interval) were studied in experiments of cats. Pentobarbital moderately reduced the mean values of both intervals and significantly reduced their standard deviations and spectral powers in all frequency bands (high-frequency, low-frequency, and very low-frequency). Pentobarbital treatment led to deceleration of breathing, the frequency range of respiratory oscillations of RR and AV intervals shifted in some cases from high to low frequencies; evaluation of spectral power in the intermittent band corresponding to respiration frequency (instead of standard fixed high-frequency band) showed that pentobarbital suppressed the respiratory oscillations in these bands. Pentobarbital induced inversion of phase ratio between respiratory oscillations of RR and AV intervals: oscillations of both intervals before pentobarbital coincided by phase, while after pentobarbital injection they were in antiphase. The mechanisms of the latter phenomenon deserve further investigation. |
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Authors:
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N N Alipov; O V Sergeeva; V M Smirnov; T E Kuznetsova; N A Bobrova |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Bulletin of experimental biology and medicine Volume: 141 ISSN: 0007-4888 ISO Abbreviation: Bull. Exp. Biol. Med. Publication Date: 2006 Mar |
Date Detail:
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Created Date: 2006-10-31 Completed Date: 2006-12-29 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0372557 Medline TA: Bull Exp Biol Med Country: United States |
Other Details:
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Languages: eng Pagination: 284-7 Citation Subset: IM |
Affiliation:
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Department of Normal Physiology, Russian State Medical University, Moscow. alipov@practica.ru |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Atrioventricular Node / drug effects*, physiology Cats Electrocardiography Female Male Myocardial Contraction / drug effects* Pentobarbital / pharmacology* |
| Chemical | |
Reg. No./Substance:
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76-74-4/Pentobarbital |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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