Document Detail


Effect of pentazocine on pressor responses of epinephrine and levarterenol.
MedLine Citation:
PMID:  915755     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In rats anesthetized with pentobarbital, pentazocine potentiated the pressor response of two exogenous amines, epinephrine and levarterenol. Although the mechanism for the pentazocine-induced potentiation of the pressor amines has not been proven, it is speculated that pentazocine may increase the blood pressure response of certain amines by interacting with the sympathetic nervous system.
Authors:
G D Russi; F G Martin
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of pharmaceutical sciences     Volume:  66     ISSN:  0022-3549     ISO Abbreviation:  J Pharm Sci     Publication Date:  1977 Nov 
Date Detail:
Created Date:  1977-12-29     Completed Date:  1977-12-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2985195R     Medline TA:  J Pharm Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1652-3     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Blood Pressure / drug effects*
Drug Interactions
Epinephrine / pharmacology*
Male
Norepinephrine / pharmacology*
Pentazocine / pharmacology*
Rats
Chemical
Reg. No./Substance:
359-83-1/Pentazocine; 51-41-2/Norepinephrine; 51-43-4/Epinephrine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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