Document Detail

Effect of paracetamol on uric acid determination.
MedLine Citation:
PMID:  15637909     Owner:  NLM     Status:  MEDLINE    
The effect of paracetamol on uric acid determination using a phosphotungstate reduction method has been investigated. The results show that apparently raised values of serum uric acid may be reported in patients receiving therapeutic levels of this drug. Levels of serum uric acid were determined over a five-hour period in three patients who had received therapeutic doses of paracetamol. The assays of serum uric acid were performed by a method based on phosphotungstate reduction and by one employing uricase. The results illustrate the problems of using the former method for clinical purposes.
P Wilding; D A Heath
Related Documents :
9211189 - The recognition of lesch-nyhan syndrome as an inborn error of purine metabolism.
10028149 - Analysis of 77,000 canine uroliths. perspectives from the minnesota urolith center.
18963429 - Titrimetric microdetermination of uric acid and thioglycollic acid by amplification rea...
6778279 - Limited value of uric acid to creatinine ratios in estimating uric acid excretion.
7695069 - Atopic asthma caused by candida albicans acid protease: case reports.
420519 - Complete deficiency of adenine phosphoribosyltransferase: a third case presenting as re...
2338449 - Isolation of mammalian brain tubulin by amino-activated gel chromatography.
17806099 - Precursor-directed biosynthesis of stilbene methyl ethers in escherichia coli.
15357999 - Trends and innovations in industrial biocatalysis for the production of fine chemicals.
Publication Detail:
Type:  Case Reports; Comparative Study; Journal Article    
Journal Detail:
Title:  Annals of clinical biochemistry     Volume:  12     ISSN:  0004-5632     ISO Abbreviation:  Ann. Clin. Biochem.     Publication Date:  1975 Jul 
Date Detail:
Created Date:  2005-01-10     Completed Date:  2005-02-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0324055     Medline TA:  Ann Clin Biochem     Country:  England    
Other Details:
Languages:  eng     Pagination:  142-4     Citation Subset:  IM    
Department of Clinical Chemistry, Queen Elizabeth Medical Centre, Birmingham.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Acetaminophen / blood,  poisoning*,  therapeutic use*
Anticonvulsants / adverse effects
Autoanalysis / instrumentation,  methods*
Bromides / adverse effects
Diazepam / adverse effects
Dose-Response Relationship, Drug
Drug Interactions
False Positive Reactions
Phenobarbital / adverse effects
Phenytoin / adverse effects
Phosphotungstic Acid / diagnostic use
Severity of Illness Index
Substance-Related Disorders
Time Factors
Urate Oxidase / diagnostic use
Uric Acid / blood*
Reg. No./Substance:
0/Anticonvulsants; 0/Bromides; 103-90-2/Acetaminophen; 12067-99-1/Phosphotungstic Acid; 439-14-5/Diazepam; 50-06-6/Phenobarbital; 57-41-0/Phenytoin; 69-93-2/Uric Acid; EC Oxidase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  A sampling device for septum-sealed blood containers.
Next Document:  An appraisal of the "Vacutainer" system for blood collection.