Document Detail

Effect of palmitic and lauric acids on the phospholipid bilayer membrane conductivity.
MedLine Citation:
PMID:  9743477     Owner:  NLM     Status:  MEDLINE    
Palmitic acid increased the conductivity of BLM from mitochondrial phospholipids when they were dissolved in a mixture of decane and chlorodecane, and was ineffective when phospholipids were dissolved in decane. Lauric acid produced an increase in the membrane conductivity independently of the phospholipid type in the membrane-forming solutions (mitochondrial phospholipids, asolectin, lecithin with cholesterol) and their solvents (decane or decane with chlorodecane). The results show that discrepancies between published data concerning fatty acid effects on the BLM conductivity may be explained by differences in phospholipids, their solvents and fatty acid used.
L M Tsofina; E N Mokhova
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Bioscience reports     Volume:  18     ISSN:  0144-8463     ISO Abbreviation:  Biosci. Rep.     Publication Date:  1998 Apr 
Date Detail:
Created Date:  1998-12-02     Completed Date:  1998-12-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8102797     Medline TA:  Biosci Rep     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  91-5     Citation Subset:  IM    
Institute of Information Transmission Problems, Russian Academy of Sciences, Moscow.
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MeSH Terms
Alkanes / pharmacology
Lauric Acids / pharmacology*
Lipid Bilayers / metabolism*
Membrane Potentials / drug effects
Mitochondria, Liver / chemistry
Palmitic Acids / pharmacology*
Reg. No./Substance:
0/Alkanes; 0/Lauric Acids; 0/Lipid Bilayers; 0/Palmitic Acids; 0/Phospholipids; 124-18-5/decane

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