| Effect of palmitic and lauric acids on the phospholipid bilayer membrane conductivity. | |
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MedLine Citation:
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PMID: 9743477 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Palmitic acid increased the conductivity of BLM from mitochondrial phospholipids when they were dissolved in a mixture of decane and chlorodecane, and was ineffective when phospholipids were dissolved in decane. Lauric acid produced an increase in the membrane conductivity independently of the phospholipid type in the membrane-forming solutions (mitochondrial phospholipids, asolectin, lecithin with cholesterol) and their solvents (decane or decane with chlorodecane). The results show that discrepancies between published data concerning fatty acid effects on the BLM conductivity may be explained by differences in phospholipids, their solvents and fatty acid used. |
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Authors:
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L M Tsofina; E N Mokhova |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Bioscience reports Volume: 18 ISSN: 0144-8463 ISO Abbreviation: Biosci. Rep. Publication Date: 1998 Apr |
Date Detail:
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Created Date: 1998-12-02 Completed Date: 1998-12-02 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8102797 Medline TA: Biosci Rep Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 91-5 Citation Subset: IM |
Affiliation:
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Institute of Information Transmission Problems, Russian Academy of Sciences, Moscow. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Alkanes
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pharmacology Animals Lauric Acids / pharmacology* Lipid Bilayers / metabolism* Membrane Potentials / drug effects Mitochondria, Liver / chemistry Palmitic Acids / pharmacology* Phospholipids Rats Thermodynamics |
| Chemical | |
Reg. No./Substance:
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0/Alkanes; 0/Lauric Acids; 0/Lipid Bilayers; 0/Palmitic Acids; 0/Phospholipids; 124-18-5/decane |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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