Document Detail

Effect of orthostatic stress on umbilical Doppler waveforms in normal and hypertensive pregnancies.
MedLine Citation:
PMID:  1530017     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Our study examined the effects of orthostatic stress and maternal hemodynamics on umbilical systolic/diastolic ratios in normal and hypertensive pregnancies. STUDY DESIGN: Eighteen normal and 20 hypertensive third-trimester pregnancies were examined in the left lateral recumbent, sitting, and standing positions. Measurements included umbilical systolic/diastolic ratio, maternal blood pressure, maternal cardiac output, and maternal total peripheral resistance. RESULTS: All patients demonstrated a fall in cardiac output and a rise in total peripheral resistance with standing. No change in systolic/diastolic ratio occurred with change to the upright position in patients with normotension. Patients with hypertension exhibited a significant increase in umbilical systolic/diastolic ratio with postural change. The increase was more marked in women who had hypertension with elevated peripheral resistance. CONCLUSION: Patients with hypertension are at increased risk of elevation of systolic/diastolic ratio with postural change; women with high-resistance hypertension may be at highest risk.
T K Sorensen; S Hendricks; T R Easterling; K L Carlson; T J Benedetti
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  167     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1992 Sep 
Date Detail:
Created Date:  1992-10-22     Completed Date:  1992-10-22     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  643-7     Citation Subset:  AIM; IM    
Department of Obstetrics and Gynecology, University of Washington Medical Center, Seattle.
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MeSH Terms
Fetus / physiology
Hypertension / physiopathology*,  ultrasonography
Pregnancy Complications, Cardiovascular*
Reference Values
Ultrasonography, Prenatal
Umbilical Cord / blood supply*,  ultrasonography
Vascular Resistance
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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