Document Detail

Effect of oral high frequency ventilation by jet or oscillator on minute ventilation in normal subjects.
MedLine Citation:
PMID:  3864284     Owner:  NLM     Status:  MEDLINE    
Normal subjects were asked to breathe through an open ended tube while high frequency oscillations were superimposed on tidal breathing via a side arm, either an eight inch (20 cm) loudspeaker or a jet ventilator being used. Both systems were comfortable and well tolerated. Spontaneous minute ventilation fell by 19-46% at frequencies up to 33 Hz without a rise in transcutaneous PCO2. Maximum ventilatory savings occurred at 1.6 Hz with the jet ventilator (p less than 0.01) and at a frequency corresponding to respiratory system resonance with the loudspeaker. This suggests that during oral high frequency ventilation pulmonary gas exchange is improved and leads to more efficient carbon dioxide excretion for a given minute ventilation. This technique provides a practical and simple method of supplementing breathing in conscious subjects, and it may also have application in the management of patients with acute or chronic respiratory failure, where intubation and conventional ventilation might be avoided.
R J George; R J Winter; M A Johnson; I P Slee; D M Geddes
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Thorax     Volume:  40     ISSN:  0040-6376     ISO Abbreviation:  Thorax     Publication Date:  1985 Oct 
Date Detail:
Created Date:  1985-12-03     Completed Date:  1985-12-03     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0417353     Medline TA:  Thorax     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  749-55     Citation Subset:  IM    
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MeSH Terms
Lung / physiology*
Lung Volume Measurements
Respiration, Artificial*
Ventilators, Mechanical*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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